Abstract:

ObjectiveTo evaluate the clinical effect and value of recombinant interferonin α1b by atomization inhalation in children with moderate to severe capillary bronchiolitis. MethodsSeventyfour children with moderate to severe capillary bronchiolitis were divided into treatment group  (36 cases) and control group (38 cases) according to whether the use of recombinant interferonin α1b atomization inhalation. The same comprehensive treatment was given to both groups， but the treatment group children added recombinant interferonin α1b atomization inhalation therapy. The conditions and treatment effect of respiratory rate（RR），gasp，three depressions sign，amount of food and pulmonary signs of  two group were analyzed. ResultsThe total effective rate of treatment group was 97.4% (37/38)， higher than 86.1% (31/36) of  control group (P<0.05).ConclusionThe effect of recombinant interferonin α1b atomization inhalation in  children with moderate to severe capillary bronchiolitis is good，it shortens the period of treatment and  is  worthy of application.

Key words: bronchiolitis, recombinant interferonin α1b;atomization inhalation