Abstract: Objective  To investigate the safety and clinical efficacy of mechanical thrombectomy to acute aortic occlusive stroke. Methods  Sixtyfive patients with acute aortic occlusive stroke who admitted to the hospital from April 2016 to April 2019 were divided into   mechanical thrombectomy group (35 patients) and intravenous thrombolysis group(30 patients).  Comparison was performed in the baseline data,  recanalization rate,  NIHSS score at 24 h and 14 d after treatment,  90day neurological recovery score (90 d mRS),  intracranial hemorrhage during treatment transformation,  clinical mortality to evaluate the efficacy and safety between  two groups. Results  The NIHSS scores of  mechanical thrombectomy group were significantly lower than those of  intravenous thrombolysis group at 24 h and 14 d after treatment (P<0.05). The 90 d mRS of mechanical thrombectomy group（54.28%）   was significantly higher than that of intravenous thrombolysis group(24.33%)(P＜0.05）.The recanalization rate of mechanical thrombectomy group(85.7%) was significantly higher than that of intravenous thrombolysis group(16.67%)(P＜0.05). Conclusion  The clinical efficacy of  mechanical thrombectomy to  acute aortic occlusive stroke is better than that of intravenous thrombolysis.

Key words: brain infarction;infarction, middle cerebral artery, thrombolysis therapy;treatment outcome