Abstract: Objective   To explore the applied value of bedside pulsed wave Doppler ultrasonography joint Apgar score in the diagnosis of hypoxicischemic encephalopathy(HIE). Methods   A total of 411 normal newborn infants and 168 newborn infants with HIE were divided into three groups（newborn infants of gestational age of less than 28 weeks are not involved due to lack of enough cases）: namely，the gestational age of over 38 weeks,  gestational age of 35 to 38 weeks and gestational age of 28 to 35 weeks. Statistical analysis was done about the callosomarginal artery and middle celebral artery of peak flow velocity (Vmax),  final diastolic velocity(Vmin) and resistance index(RI) of each group,  including the 1 minute and 5 minutes of Apgar score. Results  The contrasting data in Vmin and RI of the normally newborn infants and abnormally newborn infants in the other three groups were statistically significant(P<0.05). As time passed by,  RI of both normal infants and abnormal infants showed decrease tendency,  part of which had statistical significance(P<0.05),  while the Apgar scores were all statistically significant(P<0.05). Conclusion  Pulsed wave Doppler ultrasonograhy and Apgar score are of great applied value in the diagnosis of hypoxicischemic encephalopathy in clinical treatment.  The two combined,  early diagnostic accuracy will be greatly improved.

Key words: ultrasonography, , doppler；Apgar score；hypoxiaischemia, , brain；callosomarginal artery；middle celebral artery；infant, , newborn