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Abstract: Objective To evaluate the effect of computerized cognitive training on elderly with mild cognitive impairment.Methods A randomized controlled trial on the effect of computerized cognitive training on elderly with mild cognitive impairment was searched in Chinese and English databases, and metaanalysis was performed using RevMan 5.2 software.Results A total of 12 articles were included, involving 488 patients.Metaanalysis showed that the improvement of MMSE and MoCA in the intervention group was better than that in the control group after the intervention (MD=1.78, 95%CI 0.41,3.15,P<0.05; MD=4.02, 95%CI 1.33,6.70, P<0.05), the improvement of DSF and DSB in the intervention group was better than that in the control group after the intervention(MD=1.01, 95%CI 0.39,1.64, P<0.05; MD=0.67, 95%CI 0.16,1.17, P<0.05), the improvement of delay recall in the intervention group was better than that in the control group after the intervention(MD=1.20, 95%CI 1.00,1.39 , P<0.05), But, it had no obvious effect on SF, GDS and ADL. Conclusion Computerized cognitive training can improve the global cognitive function of the elderly with mild cognitive impairment, especially attention and shortterm memory, as well as delayed memory. But, it has no obvious effect on language abilities, depressive and everyday activities. Largesample, highquality randomized controlled study still needs more verification.
Key words: mild cognitive impairment, Alzheimer's disease;computerized cognitive training
Wang Xuemei, Zhang Yuanyuan, Yu Hong, Yang Fengjuan, Li Yujie, Li Yan. Effect of computerized cognitive training in elderly with mild cognitive impairment: a metaanalysis[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2019.09.017.
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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2019.09.017
https://huicui.hebmu.edu.cn/EN/Y2019/V34/I9/843