Abstract: Objective  To summarize the clinical features and imaging findings of patients with hemichorea associated with nonketotic hyperglycaemia(HCNH),  and to explore the possible pathogenesis,  diagnosis and treatment of the disease. Methods  Retrospective analysis was performed on the case data of  three patients with HCNH admitted to the hospital recently. The three patients were treated in the department of endocrinology,  neurology and  of neurosurgery in our hospital, respectively. Meanwhile,  relevant literature were consulted for further study. Results  HCNH usually presented as a triad of nonketone hyperglycemia,  lateral chorea,  and typical imaging manifestations of head MRI or CT,  but the manifestations were not the same,  and imaging features were also  different.  And the disease also presented a diversified trend in clinical practice. All three patients were given glucoselowering drugs,  and improved with or without combination of drugs to control symptoms of chorea. Conclusion  Fast judgement and recognition of the disease is a top priority,  timely and correct control of blood glucose is the key to the treatment. When necessary,  dopamine receptor antagonists with combination therapy in the patients can accelerate improvement of the clinical symptoms. The disease prognosis is good.

Key words: hyperglycemia;chorea, diabetes mellitus, type 2