Abstract: Objective  To study the efficacy and safety of interventional therapy in patients with acute ST segment elevation myocardial infarction(STEMI) in hyperacute stage. Methods  Acute STEMI patients who underwent emergency coronary intervention were divided into hyperacute group (49 cases) and control group (56 cases) according to the onset time of acute myocardial infarction and the level of troponin before the intervention. The success rate of stent implantation,the incidence of complications during the intraoperative and perioperative period, and the followup results of major adverse cardiac eventsone year after the operation in two groups were observed and compared.The risk factors were analyzed by logistic regression analysis. Results  The success rate of stent implantation in hyperacute group was higher than that incontrol group, whilethe incidences of complications during the intraoperative  and perioperative period, and the major clinical adverse cardiac events one year after the operation were lower in hyperacute group. There were statistically significant differences (P<0.05). Logistic regression analysis showed that preoperative troponin (OR=4.377, 95%CI: 1.29214.826, P=0.018)  was an independent predictor for major clinical adverse cardiac events in STEMI patients one year after the emergency stenting. Conclusion  Emergency coronary intervention is effective and safe for STEMI patients in hyperacute stage, and early emergent PCI can further reduce the incidence of major clinical adverse cardiac events.

Key words: coronary disease;angioplasty, , transluminal, , percutaneous coronary;troponin