Predictive value of body composition and anthropometry for dyslipidemia in postmenopausal women

doi:10.3969/j.issn.1004-583X.2022.08.006

Abstract

Abstract:

Objective To investigate the predictive value of body composition and anthropometry for dyslipidemia in postmenopausal women. Methods In the cross sectional study, postmenopausal women(n=201) who participated in the physical examination in our hospital during the same period were enrolled. Anthropometric measurements were performed by a professional clinical nutritionist, while the bioelectrical impedance was used to analyze human body composition.At the same time, medical history data and laboratory test results were collected; waist-hip ratio, waist-height ratio, skeletal muscle mass index(SMI), total cholesterol/high density lipoprotein ratio(TC/HDL-C) were obtained by data conversion, aiming to comprehensively analyze the influence of the above indexes on the blood lipid of postmenopausal women. Results The prevalence of dyslipidemia in postmenopausal women was 68.7%, of which, the rates of TG, TC, LDL-C increased and HDL-C decreased, for 48.8%, 34.8%, 22.4% and 19.4% respectively.Body mass index(BMI), body fat and fat percentage, visceral fat area, waist and hip circumference, waist-height ratio, waist-hip ratio were all positively correlated with TG and TC/HDL-C ratio (P<0.05). SMI was negatively correlated with TG, while body fat percentage, waist to height ratio and waist to hip ratio were positively correlated with LDL-C(P<0.05). Multivariate analysis found that the percentage of body fat of postmenopausal women was an independent risk factor for increased TG and LDL-C(P<0.01), waist-height ratio had significant effect on TC/HDL-C ratio(P<0.01). Waist-hip ratio was the predictor of dyslipidemia in postmenopausal women(OR=1.124,95%CI:1.062-1.190). Conclusion The prevalence of dyslipidemia in postmenopausal women is high, while in composition analysis, anthropometry measured body fat percentage, waist-height ratio and waist-hip ratio are all closely related to it. Among them, waist-hip ratio is an effective predictor for dyslipidemia in postmenopausal women, which has reference value for early warning of dyslipidemia and monitoring of lipid level.

Key words: dyslipidemia, postmenopausal women, body composition, anthropometry

CLC Number:

R589.2

Zhang Shu, Bao Yun, Chen Fang, Shan Qing. Predictive value of body composition and anthropometry for dyslipidemia in postmenopausal women[J]. Clinical Focus, 2022, 37(8): 708-712.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2022.08.006

https://huicui.hebmu.edu.cn/EN/Y2022/V37/I8/708

Figures/Tables 4

指标	血脂正常组( $n$ =63)	血脂异常组( $n$ =138)	$F$ / $Z$ /χ²值	$P$ 值
年龄[M(Q), 岁]	72.00(14.00)	70.00(15.25)	0.041	0.839
糖尿病患病率[例(%)]	19(30.2)	39(28.3)	2.612	0.455
空腹血糖[M(Q), mmol/L]	5.54(0.95)	5.60(0.91)	-0.505	0.614
尿酸(μmol/L)	307.99±74.37	328.96±78.11	3.210	0.075
白蛋白(g/L)	42.90±1.58	42.88±1.88	0.002	0.967
TG(mmol/L)	1.08±0.44	2.11±1.32	-8.922	<0.01
LDL-C(mmol/L)	1.97±0.94	2.99±1.33	-7.254	<0.01
TC/HDL-C	2.86±0.49	4.17±0.92	87.037	<0.01
体重(kg)	58.85±10.36	62.12±10.71	3.293	0.070
BMI(kg/m²)	22.54±3.64	23.85±4.93	5.628	0.018
去脂体重(kg)	42.27±8.27	39.90±9.45	0.036	0.849
体脂肪(kg)	17.27±5.24	20.10±8.65	10.457	0.01
体脂百分比(%)	28.57±6.93	32.28±6.60	13.173	<0.01
VFA(cm²)	95.71±28.56	108.46±25.64	-3.146	<0.01
腰围(cm)	75.60±9.22	80.81±8.60	15.154	<0.01
腰高比(%)	47.18±5.52	50.44±4.88	16.586	<0.01
臀围(cm)	91.50±5.32	92.96±5.11	-1.845	0.066
腰臀比(%)	82.30±8.57	86.31±7.22	23.03	<0.01
四肢肌肉量(kg)	16.97±3.91	16.80±4.39	0.036	0.849
SMI(kg/m²)	6.53±1.02	6.50±1.03	0.160	0.873

指标	血脂正常组( $n$ =63)	血脂异常组( $n$ =138)	$F$ / $Z$ /χ²值	$P$ 值
年龄[M(Q), 岁]	72.00(14.00)	70.00(15.25)	0.041	0.839
糖尿病患病率[例(%)]	19(30.2)	39(28.3)	2.612	0.455
空腹血糖[M(Q), mmol/L]	5.54(0.95)	5.60(0.91)	-0.505	0.614
尿酸(μmol/L)	307.99±74.37	328.96±78.11	3.210	0.075
白蛋白(g/L)	42.90±1.58	42.88±1.88	0.002	0.967
TG(mmol/L)	1.08±0.44	2.11±1.32	-8.922	<0.01
LDL-C(mmol/L)	1.97±0.94	2.99±1.33	-7.254	<0.01
TC/HDL-C	2.86±0.49	4.17±0.92	87.037	<0.01
体重(kg)	58.85±10.36	62.12±10.71	3.293	0.070
BMI(kg/m²)	22.54±3.64	23.85±4.93	5.628	0.018
去脂体重(kg)	42.27±8.27	39.90±9.45	0.036	0.849
体脂肪(kg)	17.27±5.24	20.10±8.65	10.457	0.01
体脂百分比(%)	28.57±6.93	32.28±6.60	13.173	<0.01
VFA(cm²)	95.71±28.56	108.46±25.64	-3.146	<0.01
腰围(cm)	75.60±9.22	80.81±8.60	15.154	<0.01
腰高比(%)	47.18±5.52	50.44±4.88	16.586	<0.01
臀围(cm)	91.50±5.32	92.96±5.11	-1.845	0.066
腰臀比(%)	82.30±8.57	86.31±7.22	23.03	<0.01
四肢肌肉量(kg)	16.97±3.91	16.80±4.39	0.036	0.849
SMI(kg/m²)	6.53±1.02	6.50±1.03	0.160	0.873

指标	TG		LDL-C		TC/HDL-C
指标	$r$ 值	$P$ 值	$r$ 值	$P$ 值	$r$ 值	$P$ 值
年龄(岁)	0.070	0.323	-0.078	0.272	0.052	0.464
糖尿病患病率(%)	-0.028	0.699	-0.060	0.405	-0.023	0.754
空腹血糖(mmol/L)	0.118	0.096	0.039	0.587	0.101	0.154
尿酸(μmol/L)	0.073	0.301	0.030	0.674	-0.019	0.793
白蛋白(g/L)	-0.026	0.711	-0.016	0.824	0.030	0.668
体重(kg)	0.121	0.088	-0.007	0.917	0.219	<0.01
BMI(kg/m²)	0.250	<0.01	0.040	0.571	0.285	<0.01
去脂体重(kg)	-0.116	0.103	-0.118	0.097	0.038	0.590
体脂肪(kg)	0.355	<0.01	0.098	0.169	0.338	<0.01
体脂百分比(%)	0.420	<0.01	0.167	0.018	0.288	<0.01
VFA(cm²)	0.323	<0.01	0.086	0.227	0.304	<0.01
四肢肌肉量(kg)	-0.089	0.212	-0.124	0.080	0.006	0.933
SMI(kg/m²)	-0.142	0.045	-0.111	0.118	0.049	0.495
腰围(cm)	0.269	<0.01	0.108	0.126	0.339	<0.01
腰高比(%)	0.369	<0.01	0.160	0.023	0.384	<0.01
臀围(cm)	0.144	0.042	-0.004	0.960	0.215	<0.01
腰臀比(%)	0.300	<0.01	0.198	<0.01	0.378	<0.01

指标	TG		LDL-C		TC/HDL-C
指标	$r$ 值	$P$ 值	$r$ 值	$P$ 值	$r$ 值	$P$ 值
年龄(岁)	0.070	0.323	-0.078	0.272	0.052	0.464
糖尿病患病率(%)	-0.028	0.699	-0.060	0.405	-0.023	0.754
空腹血糖(mmol/L)	0.118	0.096	0.039	0.587	0.101	0.154
尿酸(μmol/L)	0.073	0.301	0.030	0.674	-0.019	0.793
白蛋白(g/L)	-0.026	0.711	-0.016	0.824	0.030	0.668
体重(kg)	0.121	0.088	-0.007	0.917	0.219	<0.01
BMI(kg/m²)	0.250	<0.01	0.040	0.571	0.285	<0.01
去脂体重(kg)	-0.116	0.103	-0.118	0.097	0.038	0.590
体脂肪(kg)	0.355	<0.01	0.098	0.169	0.338	<0.01
体脂百分比(%)	0.420	<0.01	0.167	0.018	0.288	<0.01
VFA(cm²)	0.323	<0.01	0.086	0.227	0.304	<0.01
四肢肌肉量(kg)	-0.089	0.212	-0.124	0.080	0.006	0.933
SMI(kg/m²)	-0.142	0.045	-0.111	0.118	0.049	0.495
腰围(cm)	0.269	<0.01	0.108	0.126	0.339	<0.01
腰高比(%)	0.369	<0.01	0.160	0.023	0.384	<0.01
臀围(cm)	0.144	0.042	-0.004	0.960	0.215	<0.01
腰臀比(%)	0.300	<0.01	0.198	<0.01	0.378	<0.01

项目	指标	B	SE	Beta	$t$ 值	$P$ 值	R²	$F$ 值
TG的影响因素	体脂百分比	0.056	0.016	0.244	3.536	<0.01	0.244	12.502
LDL-C的影响因素	体脂百分比	0.026	0.009	0.195	2.794	<0.01	0.195	7.804
TC/HDL-C的影响因素	腰高比	0.061	0.013	0.317	4.691	<0.01	0.317	22.005

项目	指标	B	SE	Beta	$t$ 值	$P$ 值	R²	$F$ 值
TG的影响因素	体脂百分比	0.056	0.016	0.244	3.536	<0.01	0.244	12.502
LDL-C的影响因素	体脂百分比	0.026	0.009	0.195	2.794	<0.01	0.195	7.804
TC/HDL-C的影响因素	腰高比	0.061	0.013	0.317	4.691	<0.01	0.317	22.005

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