Abstract: Objective  To overall explore the diagnostic and estimated value of γglutamyltransferase(GGT) in different sex of coronary heart disease(CHD)， to study the correlation with other items. Methods  The difference in GGT  in same and different sex  between test group and control group， the relationship between GGT and traditional factors were studied through the correlation analysis， the diagnostic value of GGT in CHD was evaluated by ROC curve. Results  GGT showed significant difference between different sex in control group and in female between control and test group. There was no correlation with CHD but certain correlation with TG in male. On the other hand， there was positive correlation with CHD， correlation with age， HDLC， APOA， HCY in female. The area of ROC curve in diagnosis CHD by the value of GGT in female was 0.793. Conclusion  The correlation of GGT with CHD has significant difference in different sex， there is no correlation with CHD in male， there is significant  positive correlation with CHD in female.  GGT  has great value in diagnosis CHD  in female， but there is no correlation with lesions number.

Key words: coronary disease; , sex; , γ-glutamyltransferase