Abstract: Growth hormone deficiency in children is one of the causes of short stature. Growth hormone stimulation test is an important basis for the diagnosis of growth hormone deficiency in children,  but there are also false positives.And the test, together with target indexes,is comprehensively evaluated. Growth hormone deficiency can be divided into isolated growth hormone deficiency and multiple pituitary hormone deficiency. The growth hormone therapy is effective for isolated growth hormone deficiency,  but dynamic monitoring is needed.  Multiple pituitary hormone deficiency needs hormone replacement therapy. The  growth hormone deficiency of both types may last into adulthood,  and isolated growth hormone deficiency may develop into multiple pituitary hormone deficiency,   and dynamic monitoring and followup for life is needed.

Key words: growth hormone, growth hormone stimulation test, treatment monitoring