Abstract: Retrospective analysis of the clinical manifestation,   laboratory examination,   treatment and prognosis was made in one case of childhood acute monocytic leukemia with intracranial venous sinus thrombosis. Childhood acute monocytic leukemia with intracranial venous sinus thrombosis as the first manifestation lacked the specificity. Therefore,   in active anticoagulant and antithrombotic treatment,   original disease should be detected as soon as possible to avoid missed diagnosis and misdiagnosis.

Key words: leukemia,  , monocytic, , acute； sinus , thrombosis, , intracranial；child