Abstract: Objective  To investigatethe safety and potential value of physical activity in patients with proliferative diabetic retinopathy(PDR) by comparing the differences in the form and intensity of physical activity between patients with vitreous hemorrhage and those without significant vitreous hemorrhage of PDR. Methods  A total of 67 patients who had no fibroplasia of PDR were included in the study. Of which, 36 patients with early vitreous hemorrhage(<1 month) were in study group, and 31 patients without vitreous hemorrhage were in control group. Physical activities of patients were assessed by the International Physical Activity Questionnaire(IPAQ). And age, course of diabetes, best corrected visual acuity(BCVA), height, body mass index(BMI), HbA1c, lipid and blood pressure were also measured to investigate the predisposing factors of vitreous hemorrhage and compare the difference of physical activity between two groups. Results  No vitreous hemorrhage induced by physical activity was seen in 36 patients with PDR. Many patients in study lacked some physical activity. The time and number of participants of moderate or severe physical activity, total physical activity, energy consumption,leisure and sportsrelated physical activity in study group were significantly lower than those in control group(P＜0.05). Sedentary behaviorwas significantly prolonged, and sleep time was significantly shorter in study group; BMI, triglyceride, systolic blood pressure in study group were significantly higher than those in control group(P＜0.05). Conclusion  No vitreous hemorrhage induced by physical activities was seen, and different physical activities may be safe and beneficial to the PDR patients with no fibroplasia,so reducing sedentary behavior and improving sleep quality should be advocated.

Key words: diabetes mellitus,type 2, motor activity, retinal disease, vitreous hemorrhage