Abstract:

Objective To analyze the factors affecting the antidepressant compliance of patients with somatic symptoms disorder (SSD). Methods A total of 147 patients with SSD were prospectively enrolled, thay were divided into three groups according to Morisky Medication Adherence Scale (MMAS-8) score: good compliance group (41 cases), medium compliance group (64 cases) and poor compliance group (42 cases), the differences of sex, age, education, residence, life satisfaction, economic status, social support, insight, onset time, symptom severity, comorbidity, complication, treatment effect, adverse reaction and doctor-patient relationship among the three groups were compared. Results There were no significant differences in sex, education level and onset time among the three groups (P>0.05), there were significant differences in age, residence, life satisfaction, economic status, social support, insight, symptom severity, comorbidity, complication, treatment effect, adverse reaction and doctor-patient relationship (P<0.05, P<0.01). Logistic analysis showed that high life satisfaction, good social support, self-insight, severe symptoms and good treatment effect were the protective factors of treatment compliance, complications and severe adverse reactions were risk factors for treatment compliance. Conclusion High life satisfaction, good social support, insight, severe symptoms, good treatment results will improve the treatment compliance of SSD patients, however, complications, adverse reactions will reduce treatment compliance.

Key words: somatic symptoms disorders, antidepressants, compliance, influencing factors