Abstract:

Objective To investigate the clinical characteristics and treatment of extreme thrombocytosis caused by diabetic ketoacidosis. Methods The clinical characteristics and treatment outcomes of a patient with extreme thrombocytosis caused by diabetic ketoacidosis who was treated in Shengli Oilfield Central Hospital were retrospectively analyzed. Results The present young female patient had a sudden onset of an extreme thrombocytosis, with multiple times of reporting critical values. She denied the history of thrombocytosis and other diseases of the blood system. After bone marrow biopsy and gene testing, hematological diseases were excluded, and secondary thrombocytosis caused by diabetic ketoacidosis was considered. Platelet count decreased during the treatment course. After adequate fluid rehydration and correction of ketoacidosis, platelet count returned to the normal range within 4 days, which remained normal during follow-up.Conclusion Through literature review, there is no case report of diabetic ketoacidosis with extreme thrombocytosis at home and abroad. This case report aims to provide reference to avoid misdiagnosis and excessive treatment of diabetic ketoacidosis patients with extreme thrombocytosis.

Key words: diabetic ketoacidosis, extreme thrombocytosis