Abstract:

Objective To investigate the clinical symptoms and imaging manifestations of cerebral amyloid angiopathy(CAA). Methods The clinical data of a case who was first diagnosed with CAA in psychiatric department was retrospectively analyzed. Results The 58-year-old female patient had main clinical manifestations of plain emotion, reduced speech, and memory loss, with 0.51 g/L of cerebrospinal fluid protein, 118.9 mmol/L of chlorine, weak positive in Pan's test, irregular electroencephalogram alpha wave, more slow wave, displaying diffuse intracranial microbleeding by susceptibility weighted imaging(SWI), 11 points of Montreal cognitive assessment score(MCAS), 55 points of Wechsler Intelligence Scale(WIS). The patient was managed by methylprednisolone (500 mg/d) and papaverine (90 mg/d), and the symptoms were partially improved after two months of discharge. Conclusion SWI has high clinical value in the diagnosis of CAA.

Key words: cerebral amyloid angiopath, psychiatry department, electroencephalography, cerebrospinal fluid, susceptibility weighted imaging