Abstract: ObjectiveTo investigate the abnormal incidence of serum cholesterol (TC)， triglyceride (TG)， highdensity lipoprotein cholesterol (HDLC)， lowdensity lipoprotein cholesterol (LDLC) among the midaged and elderly people of Dongxiang minority area in Gansu province and provide the basis for the prevention and treatment of cardiovascular disease such as hypertension and diabetes mellitus. MethodsQuestionnaire investigation and physical examination among 1 000 people over 45 years of Dongxiang minority area in Gansu province were carried out by stratified random sampling method. The serum levels of TC， TG， HDLC and LDLC were detected.ResultsTC and LDLC of Dongxiang were significantly higher than those of Han. Meanwhile， TC， TG and LDLC  of  60 years old  or older were significantly higher than 45 to 59 years old and middleaged people.The dyslipidemia rate of Dongxiang was significantly higher than that of Han and the rate of abnormal TG and LDLC had significant differences (P<0.05).And the dyslipidemia rate of old people over 60yearold was higher than that of 45 to 59 years old and middleaged people. At the same time， the rate of abnormal TG and LDLC had significant difference (P<0.05). The dyslipidemia rate of over 60yearold in Dongxiang and Han among the different ethnic groups were significantly higher than those of 45 to 59 years old and middleaged people. TG， HDLC and LDLC abnormal rate of elder people in Dongxiang were significantly higher than those of middle age and TG and HDLC abnormal rate of elder people in Han were significantly higher than those of middleaged people.In different age groups， dyslipidemia rate of the elder people over 60 year old in Dongxiang was significantly higher than that of Han， especially TC， TG and LDLC. And dyslipidemia rate of 45 to 59 years old and middleaged in Dongxiang were significantly higher than those of  Han， especially TG and LDLC. Fifteen factors of dyslipidemia factors were analyzed， statistically significant factors were analyzed again. The final results showed that age and nationality were the risk factors of dyslipidemia.ConclusionDyslipidemia rate of middleaged and elder people in Dongxiang county of Gansu is higher， the dyslipidemia rate of elder people in Dongxiang is significantly higher than that of  Han and the elder people  over 60 years old are significantly higher than those of 45 to 59 years old and middleaged people.Dyslipidemia of residents in Dongxiang county of Gansu has the relation with the age， nationality， smoking， high blood pressure and BMI， of which the ethnic and age factor are great impact factors.

Key words: dyslipidemias, ethinic groups;epidemiologic studies