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Diagnosis and treatment advance in marginal zone lymphoma

  

  1. Department of Hematology, Jiangsu Provincial People's Hospital, the First Affiliated Hospital of
    Nanjing Medical University, Nanjing 210029,China
  • Online:2017-12-05 Published:2017-12-14
  • Contact: Corrsponding author: Fan Lei, Email: Fanlei3014@126.com

Abstract: Indolent Bcell lymphomas deriving from marginal zone in lymph node include three specific entities: mucosaassociated lymphoid tissue  (MALT) lymphoma, splenic marginal zone lymphoma (SMZL), and nodal marginal zone lymphoma (NMZL). The clinical and molecular characteristics are distinctive for each of these entities, although some phenotypic and genetic features are overlapping. With further understanding of mechanisms of MZL, clinical diagnosis and treatment progress rapidly. This review mainly focuses on the research progresses of translational field, clinical characteristics, diagnosis and treatment in recent years.

Key words: lymphoma, lymph nodes, treatment, diagnosis