Abstract: This paper expounds the various clinical methods for debridement and repair of diabetic foot,  and enumerates the selection principles and application techniques of debridement treatment,  dressing,  autologous plateletrich gel,  negative pressure wound therapy,  and stem cell therapy. It is emphasized that the foot ulcer should be evaluated before debridement,  and corresponding treatment programs should be selected according to the characteristics of different types of wounds in different periods,  so as to improve the efficacy,  promote wound healing and shorten the course of the disease, and  reduce amputation rate.