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Clinical features of  complete  Kawasaki disease and incomplete Kawasaki disease in a single centre

  

  1. Department of Pediatrics, the First Affiliated Hospital of Jinan University, Guangzhou 510632,China
  • Online:2018-03-05 Published:2018-03-19
  • Contact: Corresponding author: Yang Fang,Email addresses: tyf@jnu.edu.cn

Abstract: Objective  To review 50 cases of complete Kawasaki disease and 16 cases of incomplete Kawasaki disease  and analyze the clinical features and laboratory results, so as to provide evidences for early diagnosis  and  treatment of Kawasaki disease. Methods  The data of 16 patients with incomplete Kawasaki disease (IKD group) and 50 patients with complete Kawasaki disease (CKD group) were analyzed from March, 2013 to July, 2017, and the clinical manifestations, laboratory indicators, and incidence of coronary artery lesion (CAL) were compared. Results   ① There were significant differences between IKD group and CKD group in the days of fever from diagnosis and age (P<0.05); ② In IKD group, the incidences of the clinical manifestations including erythematous rash,lymphadenectasis of neck, lips and tongue changes, and edema induratum and desquamation in fingers and toes were lower than those in CKD group(P<0.05); ③ There were significant differences in glutamicpyruvic transaminase (ALT), lactate dehydrogenase (LDH), aspartate aminotransferase (AST) between IKD group and CKD group (P<0.05);  ④ The incidence of coronary artery dilation was 40.0% vs 81.3% in CKD group and IKD group, respectively (P<0.05). Conclusion  The morbidity of incomplete Kawasaki disease is higher among younger boys; the incidence of coronary artery dilation is significantly higher in incomplete Kawasaki disease than in complete Kawasaki disease.

Key words: mucocutaneous , lymph , node , syndrome; cardiovascular disease; child