Abstract: Objective  To explore the influence of seasonal changes on the incidence of nosocomial infection in inpatients of neurology  department in Beijing, and to provide scientific basis for formulating effective measures for prevention and control of nosocomial infection. Methods  The incidence rate  of nosocomial infection in neurological patients admitted to Shunyi District Hospital of Beijing from October 2015 to September 2018 was retrospectively analyzed. The monthly patient admissions and nosocomial infection  during a year were compared. The influencing factors that might cause seasonal differences of nosocomial infections were compared and analyzed. Results  In 11 922 patients, 225 cases of nosocomial infection occurred within 117 229 days of total hospitalization. The incidence rate of nosocomial infection was 1.89%, and the daily rate of nosocomial infection  was 1.92‰.  February, March and November were the periods of high incidence of nosocomial infection, mainly respiratory infections. The average hospitalization days and the proportion of cerebral hemorrhage in patients with high incidence of  nosocomial infection  were higher than those in other months, with statistically significant  difference(P<0.05). Conclusion  Early winter and early spring are the periods of  high incidence of nosocomial infection in neurology patients  in Beijing. The  prevention, control and surveillance of nosocomial infection should be strengthened  during the periods.

Key words: cross infection；Neurology, monitor, incidence, seasonal differences