Abstract: Objective  To observe the clinical efficacy of Qishenyiqi dropping pill on heart failure with preservedejection fraction. Methods   A total of 180 patients who suffer from heart failure with preserved ejection fraction were randomly divided into the conventional therapy group (90  cases,  with routine treatment) and the treatment group (90 cases, with routine treatment accompanied by Qishenyiqi dropping pill).  NTproBNP,  6MWT,  MLHFQ and E/A were recorded before treatment and after the treatment of 6  months.Results  Totally 169 patients were included, including 88 cases in treatment group and 81 cases in conventional therapy group. After 6 months of followup，the NTproBNP   and  MLHFQ of  treatment group were lower than those of  conventional therapy group(P<0.05). The E/A and 6MWT of  treatment group were higher than those of conventional therapy group(P<0.05). No serious adverse reactions  were observed.Conclusion  Qishenyiqi dropping pill can obviously improve cardiac diastolic function, exercise tolerance and life quality  in heart failure patients with preserved ejection fraction.

Key words: heart , failure； dropping pill, clinical efficacy