Abstract:

Objective To explore the effective treatment of hypokalemia combined with rhabdomyolysis caused by compound liquorice tablets. Methods The clinical diagnosis and treatment of 1 case of hypokalemia combined with rhabdomyolysis caused by compound liquorice tablets for treating dry cough was retrospectively analyzed, and the relevant literature was reviewed. Results A 71-year male presented for 7 days of anorexia and numbness of limbs. After admission, the medical history was inquired and laboratory tests were performed. He was diagnosed as severe hypokalemia combined with rhabdomyolysis and metabolic alkalosis caused by compound liquorice tablets. After withdrawal of the compound licorice tablets, potassium infusion and fluid replacement, the hypokalemia was corrected, and the muscle enzyme level gradually returned to normal with a good prognosis. Conclusion Hypokalemia combined with rhabdomyolysis is an adverse event of using licorice preparations, leading to acute renal failure, multi-organ dysfunction syndrome or even death. Early detection and intervention generally result in a favorable prognosis.

Key words: hypokalemia, rhabdomyolysis, compound liquorice tablets