Table of Content

05 May 2015, Volume 30 Issue 5

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Efficacy and safety of Evolocumab for lowering low density lipoprotein cholesterol:a meta-analysis

2015, 30(5):  481-485. 

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Objective To evaluate the efficacy and safety of Evolocumab for lowering low density lipoprotein cholesterol (LDL-C ). Methods Electronic databases were searched to identify all randomized controlled trials comparing Evolocumab and palcebo for hypercholes

Association of apolipoprotein E gene polymorphism with drug efficacy to statins in Chinese population:a meta-analysis

Wei Faquan;Wang Shuai;Liu Xueqian;Cheng Xifu;He Yi

2015, 30(5):  486-491. 

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Objective To assess the association of apolipoprotein E (APOE)gene polymorphisms with drug efficacy to statins in Chinese population.Methods The studies concerning association of APOE gene polymorphism with drug efficacy to statins were retrieved in datab

Change of pregnancy-associated protein A,urinary transferrin, D-dimer in patients with hypertension in pregnancy

Zhang Liyan;Liu Yangeng;Yan Yuan

2015, 30(5):  492-494495. 

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Objective To observe the significance of pregnancy-associated protein A (PAPP-A ), urinary transferrin,D-dimer in patients with hypertension in pregnancy and their correlation.Methods The study enrolled 120 patients with pregnancy-induced hypertension syn

Predictive value of body surface electrocardiogram in distinguishing infarct-related artery and location of occlusion in patients with acute inferior wall myocardial infarction

Sun Shikun;Li Nanyang;Li Xun

2015, 30(5):  495-498. 

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Objective To investigate the clinical value of body surface electrocardiogram in predicting the infarct-related artery(IRA)and location of occlusion in patients with ST elevation acute inferior myocardial infarction. Methods A total of 95 patients with ac

Correlation analysis of individualized treatment compliance and disease progression in patients with Parkinson disease

Zhao Hang;Ge Hanming;Liang Zhanhua;Wang Yan

2015, 30(5):  499-502. 

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Objective To explore the correlation of individualized treatment compliance and disease progression in Parkinson disease(PD).Methods Individualized treatment strategy was made for the patients in this study in the first visit,each patient should come back

Correlation between early rehabilitation efficacy of patients with acute cerebral infarction and H-type hypertension

Wang Hui;Li Jiamin;Zhao Suxia;Xiao Hui

2015, 30(5):  503-505. 

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Objective To analyze the relationship between early rehabilitation efficacy of patients with acute cerebral infarction and H-type hypertension.Methods The study involved a total of 123 patients with acute cerebral infarction undergoing early rehabilitatio

Clinical value of rapid shallow breathing index in predicting ventilator weaning in sleeping patients with acute exacerbation chronic obstructive pulmonary disease

Zhang Zhen;Jia Shiqiang;Peng Zhanxian;Zong Wei;Wen Shiwei;Sun Luhua;Rong Xuebing;Wang Jingjun;Dong Shimin

2015, 30(5):  506-508509. 

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Objective To assess the clinical value of rapid shallow breathing index (RSBI) in predicting ventilator weaning in sleeping patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD)and to explore the optimal weaning time excluding me

Relationship of dental plaque and ventilator associated pneumonia

Gao Weiliang;Wang Lingwei;Wu Weiyuan;Tao Weihua

2015, 30(5):  509-511. 

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Objective To investigate the relationship of dental plaque and ventilator associated pneumonia (VAP)in patients undergoing mechanical ventilation.Methods A total of 30 patients with VAP who were admitted into the intensive care unit of hospital were selec

A meta-analysis on the effects of regimen SOX versus FOLFOXs in treatment of advanced gastric cancer

Li Xu;Li Hongen;Li Jingya

2015, 30(5):  512-516517. 

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Objective S-1 is a novel oral derivative of 5-FU combined with oxaliplatin and widely used to treat the advanced gastric cancer.In this study,the clinical effects and adverse reactions will be compared between the regimens SOX and FOLFOXs for chemotherapy

Expression of miR129 in gastric adenocarcinoma and clinical significance

Mou Shibin;Gao Feng

2015, 30(5):  517-520. 

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Objective To investigate the expression of miR129 in stomach tubular adenoma,adenocarcinoma and its matched adjacent non-neoplastic tissure for its significance.Methods Fifty-five cases with gastric tubular adenoma,76 cases with gastric adenocarcinoma and

Relationship between interleukin-10,interleukin-4 gene polymorphisms and susceptibility of gastric cancer

Li Yunting;Guo Xin;Li Yanhui;Wang Ran

2015, 30(5):  521-524525. 

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Objective To investigate the relationship between IL-10, IL-4 gene polymorphisms and susceptibility of gastric cancer,also to analyze the distribution of genotype and gene frequency of IL-4 rs2070874,IL-10 rs1800871 and IL-10 rs1800872 in gastric cancer p

Relationship between cyclophilin A expression and chemosensitivities of gastric carcinoma cells in vitro

Wang Dong;Li Yong;Zhao Qun;Fan Liqiao;Tan Bibo

2015, 30(5):  525-528. 

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Objective To analyze the relationship between chemosensitivities of gastric cancer cell,drug-resistant related protein and protein expression of cyclophilin A (CypA)in vitro,and to explore its significance. Methods In 94 tissues of gastric cancer,the chem

Functional changes of intestinal mucosal barrier in patients with severe stroke

Wang Huiling;Jiang Yuantao;Zhang Hong;Song Yueping;Li Haihui;Ran Xiaofang;Li Zhenzhong;Zhang Haijing;Su Yanchao

2015, 30(5):  529-531532. 

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Objective To explore the functional changes of intestinal mucosal barrier in patients with severe stroke.Methods A total of 67 patients with severe stroke were enrolled in this study.Based on affected sites,all cases were divided into brainstem hemorrhage

Cystatin-C level in acute pancreatitis leading to systemic inflammatory response syndrome resulted multiple organ dysfunction syndrome patients

Sun Long;Cai Duxiong

2015, 30(5):  532-535. 

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Objective To observe the change of cystatin-C (Cys-C)in acute pancreatitis (AP)leading to systemic inflammatory response syndrome (SIRS)which causes multiple organ dysfunction syndrome (MODS). Methods A total of 1 78 AP cases were divided into three group

Diagnostic value of urinary liver-type fatty acid binding proteins and urinary neutrophil gelatinase-associated lipocalin in severe sepsis patients with acute kidney injury

Niu Kaiya;Yang Fan;Yang Xiaoyan;Ye Jun;Cheng Jiejing

2015, 30(5):  536-539. 

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Objective To investigate the early diagnosis value of urinary liver-type fatty acid binding proteins (uL-FABP)and urinary neutrophil gelatinase-associated lipocalin(u-NGAL)in severe sepsis patients with acute kidney injury(AKI).Methods Sixty patients with

Effects of neutrophil extracellular traps and contact system in uremic patients with acute coronary syndrome

Yu Qin;Xing Guangqun;Zhou Quan

2015, 30(5):  540-543544. 

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Objective To investigate the mechanism of neutrophil extracellular traps(NETs)and contact system in uremic patients with acute coronary syndrome(ACS).Methods Uremic patients were divided into uremia ACS group (subdivided into uremia ACS infection group [g

Correlation between MTNR1B gene rs10830963 polymorphism and type 2 diabetes mellitus in Gansu Bao-an population

Shi Xiue;Peng Xijia;Wang Zhongtai;Ma Jialing

2015, 30(5):  544-547. 

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Objective To explore the association between melatonin receptor 1B(MNTR1B)gene rs10830963 polymorphism and type 2 diabetes mellitus (T2DM)in Gansu Bao-an population.Methods A case-control study design was adopted and genotype and allele distribution of rs

Clinical investigation of rheumatoid arthritis in patients with Sjogren Syndrome

Qin Si;Lu Yahua

2015, 30(5):  548-551. 

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Objective To investigate the clinical and serologic features of rheumatoid arthritis (RA)in patients with Sjogren syndrome (SS)in comparison with primary Sjogren syndrome (pSS)and rheumatoid arthritis (RA). Methods Forty-seven RA patients with SS (RA-SS),

Clinico-epidemiologic characteristics,prevention and treatment of scrub typhus in Zhongshan area of Guangdong

Zheng Weihua;Chen Haibin;Hou Liusheng;Ou Lijuan;Zhao Runmei;Zhao Shuangbiao

2015, 30(5):  552-555. 

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Objective To explore the clinical and epidemiologic characteristics of scrub typhus in Zhongshan area for evidence for early diagnosis and treatment.Methods A total of 1 98 patients with scrub typhus were analyzed from various aspects, including epidemiol

Influence of doxycycline on serum IgE,protein expression of phosphorylated p38 mitogen-activated protein kinase and MMP-9 in lung tissue of asthmatic rats

Wang Liang;Li Yamei;Yang Hongshen;Meng Jing;Yang Chao;Hou Hongwei;Li Xianglan

2015, 30(5):  556-560561. 

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Objective To observe the influence of doxycycline on airway inflammation and remodeling in asthmatic rats.Methods Thirty-three SD male rats were randomly divided into three groups (1 1 rats in each group):normal control group,asthma group and doxycycline