Clinical Focus ›› 2015, Vol. 30 ›› Issue (5): 556-560561.

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Influence of doxycycline on serum IgE,protein expression of phosphorylated p38 mitogen-activated protein kinase and MMP-9 in lung tissue of asthmatic rats

Wang Liang;Li Yamei;Yang Hongshen;Meng Jing;Yang Chao;Hou Hongwei;Li Xianglan   

  • Online:2015-05-05 Published:2015-05-05

Abstract: Objective To observe the influence of doxycycline on airway inflammation and remodeling in asthmatic rats.Methods Thirty-three SD male rats were randomly divided into three groups (1 1 rats in each group):normal control group,asthma group and doxycycline

Key words: asthma, airway remodeling, doxycycline, matrix metalloproteinase 9, immunoglobulin E, p38 mitogen-activated protein kinase, rats