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ST段抬高型急性心肌梗死诱发恶性室性心律失常的危险因素

  

  1. 临夏市民族医院 内科,甘肃 临夏 731100
  • 出版日期:2016-05-05 发布日期:2016-05-04
  • 通讯作者: 拜成雄,Email:2775165869@qq.com

Analysis about risk factors of malignant ventricular arrhythmias of STelevation myocardial infarction

  1. Department of  Internal  Medicine, Linxia National Hospital, Linxia 73110,China
  • Online:2016-05-05 Published:2016-05-04
  • Contact: Corresponding author:Bai Chengnxiong,Email: 2775165869@qq.com

摘要: 目的 探讨ST段抬高型急性心肌梗死诱发恶性室性心律失常(MVA)的危险因素。方法 回顾分析就
诊于我院并确诊断为ST段抬高型急性心肌梗死患者158例,依据患者在直接PCI手术48小时后是否发生MVA 分
成研究组(发生MVA,32例)及对照组(未发生MVA,126例),统计并比较两组患者的基础临床资料指标、心电图指
标、实验室检查指标、冠状动脉造影指标等。结果 研究组糖尿病患者比例、血糖水平、肌酐水平、白细胞水平、中性粒
细胞水平以及心功能KlillipⅣ级比例均明显高于对照组(P <0.05),血钾浓度明显低于对照组(P <0.05)。ST 段
抬高型急性心肌梗死诱发MVA的危险因素包括心功能KlillipⅣ级、白细胞计数≥11.040×109/L、中性粒细胞计数
≥8.155×109/L、血糖≥9.58mmol/L、血钾≤3.13mmol/L、肌酐≥96.93μmol/L(P <0.01)。结论 针对合并有
上述危险因素的ST段抬高型急性心肌梗死患者应加强临床干预措施,降低MVA发生率,改善患者预后。

关键词: 心肌梗死, 再灌注, 心律失常, 危险因素

Abstract:

Objective To analyze the risk factors of malignant ventricular arrhythmias (MVA) of STelevation myocardial infarction. Methods Retrospective analysis was made in 158 cases of patients  in our hospital who had clear and definite diagnosis for STelevation myocardial infarction. The patients were divided into study group (MVA  incidence, 32 cases) and control group (no MVA incidence, 126 cases) according to the incidence of  MVA 48 hours after primary PCI. The clinical indicators such as basic clinical  indicators, ECG, laboratory test, coronary angiography of two groups were counted and compared. Results The proportion of patients with diabetes,the level of  blood glucose, level of serum creatinine, level of leukocyte, level of neutrophil cell and proportion of  heart function Klillip grade Ⅳ of patients in study group were significantly higher than those in control group (P<0.05), while the serum potassium concentration was significantly lower than that of control group (P<0.05).The risk factors of  MVA of STelevation myocardial infarction included heart function Klillip grade Ⅳ, leukocyte count was greater than or equal to 11.040×109/L,neutrophils count was greater than or equal to 8.155×109/L, the level of blood glucose was more than or equal to 9.58  mmol/L, serum potassium was less than or equal to 3.13  mmol/L, creatinine was more than or equal to  96.93  μmol/L(P<0.01). Conclusion  The clinical intervention measures of STelevation myocardial infarction in view of the above risk factors should be strengthened, the incidence of  MVA will be reduced, the prognosis of patients will be improved.

Key words: myocardial infarction, reperfusion; , arrhythmia, risk factors