雾化吸入重组干扰素α1b治疗中重度毛细支气管炎患儿疗效

doi:10.3969/j.issn.1004-583X.2016.06.019

临床荟萃

雾化吸入重组干扰素α1b治疗中重度毛细支气管炎患儿疗效

邯郸市妇幼保健院儿科,河北邯郸 056001

收稿日期:2016-03-22 出版日期:2016-06-05 发布日期:2016-06-06
通讯作者: 通信作者:黄广丽,Email:hgl731115@163.com

Effect of recombinant interferonin α1b by atomization inhalation in children with moderate to severe capillary bronchiolitis

Department of Paediatrics，Handan Maternity and Child Care Hospital，Handan 056001，China

Received:2016-03-22 Online:2016-06-05 Published:2016-06-06
Contact: Corresponding author: Huang Guangli，Email：hgl731115@163.com

摘要/Abstract

摘要： 目的探讨雾化吸入重组干扰素α1b治疗中重度毛细支气管炎的临床疗效及价值。方法回顾性分
析我科收治的中重度毛细支气管炎患儿74例,根据是否采用雾化吸入重组干扰素α1b分成对照组36例和治疗组38
例,两组均给予对症、支持及支气管舒张剂雾化吸入等治疗,治疗组在上述基础上加雾化吸入重组干扰素α1b治疗,分
析两组患儿呼吸频率、喘息、三凹征、饮食量及肺部体征等情况及治疗效果。结果治疗组总有效率97.4%(37/38),
高于对照组的86.1%(31/36)(P <0.05)。结论雾化吸入重组干扰素α1b治疗中重度毛细支气管炎疗效显著,缩
短疗程,值得临床推广。

关键词: 细支气管炎, 重组干扰素&alpha, 1b, 雾化吸入

Abstract:

ObjectiveTo evaluate the clinical effect and value of recombinant interferonin α1b by atomization inhalation in children with moderate to severe capillary bronchiolitis. MethodsSeventyfour children with moderate to severe capillary bronchiolitis were divided into treatment group (36 cases) and control group (38 cases) according to whether the use of recombinant interferonin α1b atomization inhalation. The same comprehensive treatment was given to both groups， but the treatment group children added recombinant interferonin α1b atomization inhalation therapy. The conditions and treatment effect of respiratory rate（RR），gasp，three depressions sign，amount of food and pulmonary signs of two group were analyzed. ResultsThe total effective rate of treatment group was 97.4% (37/38)， higher than 86.1% (31/36) of control group (P<0.05).ConclusionThe effect of recombinant interferonin α1b atomization inhalation in children with moderate to severe capillary bronchiolitis is good，it shortens the period of treatment and is worthy of application.

Key words: bronchiolitis, recombinant interferonin α1b;atomization inhalation

黄广丽,石庆生,李军勤,陈素萍,王鸣飞. 雾化吸入重组干扰素α1b治疗中重度毛细支气管炎患儿疗效[J]. 临床荟萃, doi: 10.3969/j.issn.1004-583X.2016.06.019.

Huang Guangli， Shi Qingsheng，Li Junqin，Chen Suping，Wang Mingfei. Effect of recombinant interferonin α1b by atomization inhalation in children with moderate to severe capillary bronchiolitis[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2016.06.019.

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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2016.06.019

https://huicui.hebmu.edu.cn/CN/Y2016/V31/I6/666

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雾化吸入重组干扰素α1b治疗中重度毛细支气管炎患儿疗效

Effect of recombinant interferonin α1b by atomization inhalation in children with moderate to severe capillary bronchiolitis

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