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乌鲁木齐天山区维吾尔族居民跟骨骨密度测定及相关因素分析

  

  1. 1.新疆医科大学第一附属医院 内分泌科,新疆 乌鲁木齐 830054;2. 乌鲁木齐兵团医院 内分泌科,新疆 乌鲁木齐 830002;
    3. 乌鲁木齐米东区人民医院  内科,新疆 乌鲁木齐 830000
  • 出版日期:2017-04-05 发布日期:2017-03-31
  • 通讯作者: 通信作者:蒋升,Email: xjjsh@126.com
  • 基金资助:
    新疆维吾尔自治区自然科学基金项目(2014211C058)

Measurement of calcaneus bone mineral density and relationship analysis in Uygur residents in Tianshan community of Urumqi

  1. 1.Department of Endocrinology, the First Affiliated Hospital of Xinjiang Medical University,
    Urumqi 830054, China; 2.Department of Endocrinology, Xinjiang Corps Hospital, Urumqi 830002, China;
    3.Department of Internal Medicine, Xinjiang Midong People's Hospital, Urumqi 830000, China
  • Online:2017-04-05 Published:2017-03-31
  • Contact: Corresponding author:Jiang Sheng, Email: xjjsh@126.com

摘要: 目的了解乌鲁木齐天山区维吾尔族居民骨密度情况及其影响因素,为本社区骨质疏松的预防和干预提供基本信息和依据。方法测量乌鲁木齐天山区773例18~82岁维吾尔族居 民跟骨骨密度。比较不同性别各年龄段骨质疏松发病率,同时,检测内脏脂肪面积、体脂百分比、腰臀比、体脂量、肌肉重量,计算肌肉率,并进行问卷调查,检测空腹血糖、餐后2小时血糖、甘油三酯(TG)、高密度脂蛋白胆固醇(HDLC)、低密度脂蛋白胆固醇(LDLC)、总胆固醇(TC);计算其体质量指数(BMI)、腰臀比。结果随着年龄的增加男、女骨质疏松发病率均逐渐增加(P<0.01),女性骨质疏松发病率高于男性,但差异无统计学意义(P>0.05),女性在50岁左右及70岁左右骨质疏松发病率增加较明显。回归分析显示,男性增龄、内脏脂肪面积增加为骨质异常可能的危险因素,BMI增加为其可能的保护因素;女性绝经、增龄、腰臀比增加为骨质异常可能的危险因素,BMI增加 、肌肉率增大为其可能的保护因素。结论乌鲁木齐天山区男性保持一定的BMI的同时应低脂饮食、适当运动,减少内脏脂肪面积以预防骨质异常的发生、发展。女性应尽可能避免人工绝经、腹型肥胖,增强运动增加肌肉量,减低腹部脂肪量有助于预防骨质异常的发生、发展,从而预防骨质疏松及骨质疏松性骨折的发生。

关键词: 骨质疏松, 骨密度, 跟骨, 危险因素

Abstract: ObjectiveTo explore the bone mineral density and the relevant factors in Uighur residents  in Urumqi Tianshan district and to provide basic information and basis for osteoporosis prevention and intervention in this community.MethodsCalcaneal bone mineral density was measured for 773 uighurs in Urumqi Tianshan. The osteoporosis incidence of different genders was compared, meanwhile, visceral fat area, body fat percentage, waist hip ratio, body fat mass, muscle weight, calculating rate of muscle, questionnaire investigation, fasting blood glucose, blood sugar 2 hours after meal, triglycerides (TG), highdensity lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol(LDL-C), total cholesterol(TC),body mass index (BMI) and waist hip ratio were detected. ResultsThe incidence of osteoporosis increased significantly with the age  in male and female(P<0.01),osteoporosis incidence was higher in female than in male, at the age 50 and 70 years, the osteoporosis incidence increased obviously .Regression analysis showed that the increased age and visceral fat area in male may be risk factors for bone abnormality and the increased BMI in male may be protection factor for bone abnormality; the increased age, menopause and waisttohip ratio in female may be risk factors for bone abnormality, increased BMI and rate of muscle may be protection factors. ConclusionIn Tianshan of Urumqi area, in male, low fat diet, proper exercise and lowing visceral fat area should be performed in order to prevent the occurrence and development of bone abnormalities. Female should try to avoid artificial menopause and abdominal obesity, enhance movement,increase muscle mass, reduce abdominal fat to prevent the occurrence and development of abnormal bone, so as to prevent the occurrence of osteoporosis and osteoporotic fracture.

Key words: osteoporosis;bone density, calcaneus;risk factors