临床荟萃

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急性心肌梗死合并心脏破裂的临床特点

  

  1. 毫州市人民医院  心内科,毫州 236800
  • 出版日期:2017-08-05 发布日期:2017-08-10
  • 通讯作者: 通信作者:董松武,Email:dongsongwu@163.com

Clinical characteristics of cardiac rupture after acute myocardial infarction

  1. Department of Cardiology, Bozhou People’s Hospital, Bozhou 236800,China
  • Online:2017-08-05 Published:2017-08-10
  • Contact: Corresponding author: Dong Songwu,Email:dongsongwu@163.com

摘要: 目的  分析急性心肌梗死(AMI)患者出现心脏破裂(CR)并发症的临床特征、发病危险因素,以早期识别心脏破裂高危患者及减少该并发症发生。方法  回顾性分析2014年9月至2016年10月亳州市人民医院心内科收治并确诊AMI  1 110例临床资料,其中合并CR患者37例为研究组,以1∶3随机抽取同期住院的非CR的AMI患者111例为对照组。统计两组临床资料,采用Logistic回归分析方法分析具有心脏破裂预测价值的相关危险因素。结果  CR组患者年龄(72.92±7.84)岁  vs (66.25±10.05)岁(P<0.05),女性占比(51.35% vs  26.13%,P<0.05),就诊时间7(5,48)h  vs 5(3,12)h(P<0.05),心率(85.30±23.02)次/min  vs (76.53±16.41)次/min(P<0.05),TG  0.99(0.86,1.36) mmol/L  vs  1.35(1.00,1.95) mmol/L(P<0.05),再灌注比例5例(13.51%)vs 43例(38.74%)(P<0.05),及同时使用血管紧张素转化酶抑制剂(ACEI)和β阻滞剂比例10例(27.03%) vs  52例(46.85%)(P<0.05),较对照组差异有统计学意义;Losgistic回归分析提示高龄及未联合使用ACEI和β阻滞剂是独立危险因素(P<0.05)。AMI发生CR平均时间为(4.65±3.37)天。CR发生前41.67%患者有异常诱因。结论  高龄、女性、就诊时间延迟、入院心率增快、低TG、未灌注治疗及未联合ACEI和β阻滞剂是AMI合并CR高危人群,高龄及未联合ACEI和β阻滞剂是独立危险因素。尽早、完全的梗死相关动脉再灌注,尽早联合使用ACEI和β阻滞剂,避免情绪波动及下床活动可减少AMI合并CR的发生。

关键词: 心肌梗死, 心脏破裂, 危险因素

Abstract: Objective  To analyze the clinical features and risk factors of cardiac rupture (CR) complications in patients with acute myocardial infarction (AMI), and to identify the risk factors for early identification of cardiac rupture and to reduce the incidence of complications. Methods  The clinical data of 1 110 cases of AMI admitted to the hospital from September 2014 to November 2016 were reviewed, and 37  cases combined with CR assigned into study group, and 111 cases from 1∶3  pairmatched randomly in non CR AMI patients were control group. Clinical information was compared between two groups and the relevant risk factors for predicting CR were studied by logistic regression analysis. Results  The two groups showed statistical significances in the age of patients (72.92±7.84) years old vs (66.25±10.05) years old (P<0.05), the proportion of women (51.35% vs 26.13%,P<0.05), the treatment time 7 (5,48) h vs 5 (3,12) h(P<0.05), heart rate (85.30±23.02) beats/min vs  (76.53±16.41) beats/min(P<0.05), TG 0.99(0.86,1.36) mmol/L vs 1.35(1.00,1.95) mmol/L(P<0.05), reperfusion ratio 5 cases (13.51%) vs 43 cases(38.74%)(P<0.05) and using angiotensinconverting enzyme inhibitor(ACEI) and beta blockers ratio 10 cases (27.03%) vs 52 cases(46.85%)(P<0.05). Logistic multifactor regression analysis suggested that the age and not using of ACEI and beta blockers were independent risk factors. The mean time of incidence of CR after AMI was (4.65±3.37) days, and 41.67% of AMI had abnormal incentives before the onset of CR. Conclusion  Advanced age, women, treatment time delay, high admission heart rate, low TG, without infusion therapy and not using of ACEI and beta blockers were high risks for CR. Advanced age and not using of ACEI and beta blockers were independent risk factors.Early reperfusion of infarct related artery completely, early using of ACEI and beta blockers, avoiding mood swings and ambulation could reduce the incidence of CR after AMI.

Key words: myocardial infarction, heart rupture, risk factors