临床荟萃

• 专题 • 上一篇    下一篇

肝肾综合征的诊治现状

  

  1. 河北医科大学第二医院 消化内科 河北省消化病实验室  河北省消化病研究所, 河北 石家庄 050000
  • 出版日期:2018-11-05 发布日期:2018-12-10
  • 通讯作者: 通信作者:姜慧卿,Email:jianghq@aliyun.com
  • 作者简介:姜慧卿,医学博士、河北医科大学第二医院二级教授、主任医师、博士生导师。河北省消化病研究所所长,河北省消化病重点实验室主任。享受国务院政府特贴。中华医学会消化内镜学分会常委,中国医师协会内镜医师分会常委,中国医师协会消化病学分会委员,河北省医师协会消化内镜医师分会主委,河北省医学会消化病学分会侯任主任委员。主要研究方向为慢性肝病、消化系疾病内镜介入诊治。承担省自然基金、国家自然基金和科技厅等课题10项,获省部级奖励5项,其中河北省科技进步一等奖1项,发表论文150余篇,SCI收录论文30篇,主编参编教材和医学专著15部。

Current status of diagnosis and treatment of hepatorenal syndrome

  1. Department of Gastroenterology,  the Second Hospital of Hebei Medical University,  Hebei Key Laboratory
    of Gastroenterology,  Hebei Institute of Gastroenterology,  Shijiazhuang 050000,  China
  • Online:2018-11-05 Published:2018-12-10
  • Contact: Corresponding author: Jiang Huiqing, Email: jianghq@aliyun.com

摘要: 肝肾综合征(HRS)是晚期肝硬化患者的极危重并发症,患者肾脏无明显器质性病变,是以肾功能损伤、血流动力学改变和内源性血管物质异常为特征的一种综合征。HRS显著增加肝硬化患者病死率。其早期诊断和及时治疗对降低病死率、改善预后至关重要。目前,HRS的诊断主要以血肌酐标准为主。肝移植仍是解决HRS最根本的治疗手段。未来仍需对HRS的基础与临床方面努力专研,以求突破。

关键词: 肝肾综合征, 诊断, 治疗

Abstract: Hepatorenal syndrome (HRS) is a critical complication of patients with advanced cirrhosis,  which is characterized by renal dysfunction,  hemodynamic changes and endogenous vascular substance abnormalities with the patients presenting  no substantial renal damage. It can significantly increase mortality in cirrhotic patients, which makes early diagnosis and timely treatment of HRS essential. Currently,  diagnosis of HRS is mainly based on serum creatinine criteria. Liver transplantation remains the only means of HRS. Further researches centered on its foundation and clinical manifestation should be conducted in the future so as to make some breakthrough.

Key words: hepatorenal syndrome, diagnosis, treatment