关键词: 新型冠状病毒肺炎, 方舱医院, 临床特征

Abstract: Objective  To analyze the clinical characteristics and outcome of coronavirus disease 2019(COVID19) in Wuhan Jiangan Makeshift (Fangcang) Hospital for reference in prevention and treatment of this disease. Methods  Retrospective analysis was conducted on the clinical data of 472 COVID19 patients admitted to Wuhan JiangAn Makeshift (Fangcang) Hospital from February 12 to March 8,  2020 to see whether there were differences among COVID19 patients,  discharged and transferred patients in terms of the age,  first clinical symptoms,  chest CT findings and complications. Results  Of 472 patients,  the ratio of males (215) to females (257) was 1∶1.2. The first clinical symptoms were mainly fever (75.4%),  dry cough (50.0%) and fatigue (20.1%). There were 87 patients (18.4%) with chronic basic diseases. A total of 37 (7.8%) patients with positive nucleic acid showed no clinical symptoms,  and two of them were transferred  for further treatment. Totally 31 patients(6.5%)  with positive nucleic acid had no abnormal chest CT findings and were discharged from the hospital. And 57 patients (12.1%) became sicker and were transferred for further treatment. No deaths were reported. There were statistically significant differences between the discharged and the transferred patients in fever,  dry cough,  chest tightness,  soreness,  diarrhea and chills（P＜0.05）. Among the patients having clinical symptoms with fever as the first symptom,  there were statistically significant differences in terms of low fever,  high fever and ultrahigh fever (P＜0.05）. There were statistically significant differences between discharged patients and transferred patients in terms of the diffuse distribution of chest CT lesions in both lungs,  the involvement of lesions in a single lobe,  multiple lesions,  single lesion and no abnormalities（P＜0.05）. Novel coronavirus specific antibodies (IgG,  IGM) were tested in 46 patients,  of which  eight cases were tested positive for IGM and IgG,  38 cases were tested negative for IGM and positive for IgG,  and 0 was tested negative for both antibodies. Conclusion  COVID19 highrisk population are mainly concentrated on old people with many basic diseases,  chest CT manifestations of diffuse lesions,  the first clinical symptoms with fever (especially high fever),  dry cough,  chest tightness,  body aches,  diarrhea and chills. And they are easy to progress to (critically) ill patients.

Key words: COVID19, Makeshift (Fangcang) hospital, Clinical characteristics