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中青年和老年疑似冠心病患者冠状动脉病变特点比较

  

  1. 保定市第一中心医院 心血管内二科,河北 保定 071000
  • 出版日期:2020-04-20 发布日期:2020-04-16
  • 通讯作者: 张旗,Email: zhangqixxgnek@126.com

Comparison of coronary artery lesions in the youth and elderly patients  with suspected coronary artery disease

  1. Department of Cardiology,  Baoding No. 1 Central Hospital,  Baoding 071000,  China
  • Online:2020-04-20 Published:2020-04-16
  • Contact: Corresponding author: Zhang Qi, Email: zhangqixxgnek@126.com

摘要: 目的  应用256排冠状动脉CT分析中青年和老年疑似冠心病患者冠状动脉病变特点。方法  2018年6月至2018年11月因疑诊冠心病在保定市第一中心医院就诊并行冠状动脉CT检查为冠状动脉病变的患者972例。根据年龄分为中青年组(<60岁,528例)和老年组(≥60岁,444例),比较两组危险因素及冠状动脉病变特点。结果  中青年组男性比例、体重指数(BMI)、吸烟、三酰甘油(TG)水平明显高于老年组;老年组高血压比例明显高于中青年组(P<0.05)。老年组钙化斑块及混合斑块所占比例高于中青年组(均P<0.01)。中青年组主要为单支,低钙化积分病变,而老年组主要为多支,高钙化积分病变。Logistic回归分析显示中青年组高钙化积分的独立危险因素依次为吸烟、高血压、糖尿病,而老年组高钙化积分的独立危险因素依次为糖尿病、性别构成。结论  不同年龄段的冠状动脉病变特点有其自身的临床特征。

关键词: 冠状动脉病变, 体层摄影术,  , 螺旋计算机, 钙化积分

Abstract: Objective  To investigate the features of coronary artery lesions in the youth and elderly patients with suspected coronary artery disease(CAD) using 256slice coronary computed tomography angiograph. Methods  A total of 972 patients with suspected  CAD  undergoing coronary computed tomography angiograph for coronary artery lesions were enrolled.  The patients were divided into youth group (age<60 years,  n=528) and elderly group(age≥60 years,  n=444),  the cardiovascular risk factors and features of coronary artery lesions of two groups were analyzed. Results  The youth group  were higher among gender,  body mass index (BMI),  smoking,  triglyceride than the elderly group; but the prevalence of hypertension was lower than the elderly group(P<0.05). The proportion of calcified plaques and mixed plaques were significantly higher in elderly group than youth group(all P<0.01).  Youth group were mainly singlevessel lesions with low calcification score,  while elderly group were mainly multivessel lesions with high calcification score. Logistic regression analysis indicated that the youthaged degree aggravating the independent risk factors of high coronary artery calcification score were smoking,  hypertension,  diabetes;  while the elderlyaged degree aggravating the independent risk factors of high coronary artery calcification score were diabetes and being male. Conclusion  The characteristics of coronary artery lesions in different age groups have their own clinical features.

Key words: coronary artery lesions, tomography; , spiral , computed, calcification score