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RDW、NLR、hs-CRP检测对急性胰腺炎严重程度的评估价值

  

  1. 1.锦州医科大学葫芦岛市中心医院 研究生培养基地,辽宁 葫芦岛 125000;
    2.锦州医科大学附属第一医院 老年医学科二病区,辽宁 锦州 121000
  • 出版日期:2020-08-20 发布日期:2020-06-24
  • 通讯作者: 王小梅,Email: wxm631229@163.com

Evaluation value of RDW, NLR and hsCRP detection on the severity of acute pancreatitis

  1. 1.Graduate Planning and Training Base,  Huludao Central Hospital,  Jinzhou Medical University,
    Huludao 125000, China; 2. Second Department of Geriatrics,  First Affiliated Hospital of
    Jinzhou Medical University,  Jinzhou 121000, China
  • Online:2020-08-20 Published:2020-06-24
  • Contact: Corresponding author:Wang Xiaomei, Email: wxm631229@163.com

摘要: 目的  探讨检测红细胞分布宽度(RDW)、中性粒细胞与淋巴细胞比值(NLR)、超敏C反应蛋白(hsCRP)水平对急性胰腺炎(AP)严重程度的评估价值。方法   根据中国急性胰腺炎诊治指南(2019年,沈阳)将175例AP患者分为轻症组和重症组。比较两组一般资料及相关指标水平。比较RDW、NLR、hsCRP及联合检测对AP严重程度的评估价值。结果   重症组RDW、NLR、hsCRP水平均高于轻症组(P<0.05)。RDW、NLR、hsCRP均可评估AP的严重程度,联合检测对AP严重程度的评估具有更高的诊断效能,其灵敏度、特异度分别为90.9%、90.8%,其曲线下面积明显高于RDW、NLR、hsCRP。结论  RDW、NLR、hsCRP 均可不同程度的评估AP的严重程度,联合检测可提高对AP严重程度的诊断效能。

关键词: 胰腺炎, 急性坏死性, 红细胞分布宽度, 中性粒细胞与淋巴细胞比值, 超敏C反应蛋白

Abstract: Objective  To explore the evaluation value of red blood cell distribution width(RDW), neutrophiltolymphocyte ratio(NLR) and hypersensitive Creactive protein(hsCRP) levels on the severity of acute pancreatitis (AP).Methods  According to the Guidelines for the Diagnosis and Treatment of Acute Pancreatitis in China (Shenyang, 2019),  175 patients with AP were divided into mild and severe groups. General information and related indicators were compared between the two groups. The evaluation value of RDW, NLR, hsCRP and combined detection for AP severity were compared. Results  The RDW, NLR and hsCRP levels in the severe group were significantly higher than those in the mild group (P<0.05). RDW, NLR and hsCRP can all assess the severity of AP. The combined detection had a higher diagnostic efficiency for the assessment of AP severity, with the sensitivity and specificity of  90.9% and 90.8%, respectively, and the area under the curve (ACU) was significantly higher than that of RDW, NLR and hsCRP. ConclusionRDW, NLR and hsCRP can all assess the severity of AP to different degrees. Combined detection can improve the diagnostic efficiency of AP severity.

Key words:  pancreatitis, acute necrotizing, red blood cell distribution width, neutrophil to lymphocyte ratio, hypersensitive Creactive protein