临床荟萃

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小儿支原体肺炎的肺外并发症临床特征和预后影响因素

  

  1. 郑州大学附属儿童医院河南省儿童医院郑州儿童医院西区医院 普内一病区,河南  郑州  450007
  • 出版日期:2020-09-20 发布日期:2020-07-09
  • 通讯作者: 张广超,Email: chao6881@126.com
  • 基金资助:
    河南省医学科技攻关计划----MP-SAT在肺炎支原体的诊断及疗效评估的应用价值(2018020632)

Clinical characteristics and prognostic factors of extrapulmonary complications  in children with mycoplasma pneumonia

  1. General  Internal  Medicine, Henan  Children's  Hospital,  Zhengzhou  450007,  China
  • Online:2020-09-20 Published:2020-07-09
  • Contact: Corresponding author: Zhang Guangchao, Email: chao6881@126.com

摘要: 目的  探讨小儿支原体肺炎(MPP)的肺外并发症临床特征和预后影响因素。方法  回顾性分析于我院儿科进行治疗的276例MPP并发肺外并发症患儿临床资料。将276患儿依据首个疗程治疗效果分为预后良好组(169例)和预后不良组(107例)。记录分析患儿肺外并发症临床表现,分析不同系统损害临床特征。将可能影响MPP合并肺外并发症患儿预后的危险因素进行单因素及多因素分析。结果  患儿肺外并发症包括消化系统症状等多个系统,以消化系统并发症所占比例最高。经单因素及多因素分析,入院前病程、C反应蛋白(CRP)、红细胞沉降率(ESR)、贫血、白蛋白<30  g/L、阿奇霉素起始使用时间、肺实变影、并发症累及多个系统等因素为影响MPP合并肺外并发症患儿预后的独立危险因素。结论  MPP可能引发多系统并发症,以消化系统并发症最为常见,入院前病程、CRP、ESR、贫血、白蛋白<30  g/L、阿奇霉素起始使用时间、肺实变影、并发症累及多个系统等因素为影响MPP合并肺外并发症患儿预后的的独立危险因素。

关键词: 肺炎,  , 支原体, 肺外并发症, 临床特征, 预后, 危险因素

Abstract: Objective  To explore the clinical characteristics and prognostic factors of extrapulmonary complications in children with mycoplasma pneumonia (MPP). Methods  The clinical data of 276 cases of MPP complicated with extrapulmonary complications were retrospectively analyzed. The patients were divided into good prognosis group (169 cases) and poor prognosis group (107 cases). The clinical manifestations of extrapulmonary complications were recorded to  analyze different system damage. The singlefactor and multiplefactor analysis were conducted to analyze the risk factors that may affect the prognosis of MPP children with extrapulmonary complications. Results  Extrapulmonary complications in children occurred in digestive system and other systems,  and digestive complications accounted for the highest proportion. The singlefactor and multiplefactor analysis showed that the independent risk factors which affected the prognosis of children with MPP complicated with extrapulmonary complications were the course before admission,  CRP,  ESR,  anemia,  albumin <30 g/L,  initial usage time of azithromycin,  pulmonary consolidation,  complications involving multiple systems. Conclusion  MPP may cause multiple system complications,  and digestive system complications were the most common. The independent risk factors that affected the prognosis of MPP children with extrapulmonary complications included preadmission course,  CRP,  ESR,  anemia,  albumin < 30 g/L,  initial usage time of azithromycin,   pulmonary consolidation and complications involving multiple systems.

Key words: pneumonia, , mycoplasma, extrapulmonary complications, clinical characteristics, prognosis, risk factors