Relationship between blood glucose variability and prognosis in patients with acute organophosphorus pesticide poisoning

doi:10.3969/j.issn.1004-583X.2016.01.019

Abstract

Abstract: Objective To investigate the relationship between blood glucose variability and prognosis in patients with acute organophosphorus pesticide poisoning (AOPP).Methods A retrospective study involving 59 patients with AOPP from January 2010 to August 2015 was performed. All cases were divided into survival group (n=40) and death group (n=19) according to the prognosis. Blood glucose (GLU), the mean and standard deviation of GLU (GLUave and GLUsd), variation of GLU (GLUcv), GLU lability index (GLI) and APACHEⅡ score were monitored and calculated. The value of prognosis of each index was evaluated by receiver operating characteristic (ROC) curve.Results There was no statistically difference in the GLU admission and GLUave between two groups (P>0.05). The levels of GLUsd,GLUcv and GLI in death group were significantly higher than those of survival group (P<0.05). ROC curve indicated that GLI was most sensitive in predicting prognosis and was similar to APACHⅡ score.Conclusion Glucose variability is firmly associated with mortality in patients with AOPP, lowering blood glucose variability is helpful in improving outcomes in AOPP patients.

Key words: poisoning, glucose variability

CLC Number:

R595.9

Qiu Bin,Xu Jianru, Ge Zhihua. Relationship between blood glucose variability and prognosis in patients with acute organophosphorus pesticide poisoning[J]. Clinical Focus, 2016, 31(1): 74-76.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2016.01.019

https://huicui.hebmu.edu.cn/EN/Y2016/V31/I1/74

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