Lowdensity lipoprotein cholesterol and mortality in the elderly--a meta analysis

doi:10.3969/j.issn.1004-583X.2017.09.014

Abstract

Abstract: Objective To systematically evaluate the association between lowdensity lipoprotein cholesterol (LDLC) and mortality.Methods The Pubmed， Cochrane Library， CNKI， CBM and Wangfang databases were searched from building databases to December 2016. The enrollment involved screening cohort studies with OR values and 95% CI or the relevant data which can be calculated.Results Five studies with 50 361 participants were finally included. High LDLC as reference: the pooled RR was 1.405（95%CI=1.2061.635，P<0.01）. Low LDLC as reference:　the pooled RR was 0.552 （95%CI=0.5060.602，P<0.01）. With the change of LDLC， the risk of mortality became inverse. Conclusion High LDLC is inversely associated with the allcause mortality in the elderly.

Key words: coronary artery disease, lowdensity lipoprotein cholesterol, elderly, mortality

Liu Jianping1， Liu Yan1， Wu Yuhuai1， Liu Jianwei2. Lowdensity lipoprotein cholesterol and mortality in the elderly--a meta analysis[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2017.09.014.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2017.09.014

https://huicui.hebmu.edu.cn/EN/Y2017/V32/I9/793

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Lowdensity lipoprotein cholesterol and mortality in the elderly--a meta analysis

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