Abstract: Objective  To explore the relatioanship between brachialankle pulse wave velocity(baPWV) and risk factors for arteriosclerosis in middleaged and elderly patients. Methods  The patients who admitted in the hospital from 2012 to 2016 were analyzed in  baPWV. The inclusion criteria of 186 cases were recruited into this survey.According to the baPWV levels， the patients were divided into two groups：  arteriosclerosis group(baPWV≥1 400 cm/s) and normal group(baPWV＜1 400 cm/s).The correlation between baPWV and risk factors for arteriosclerosis was analyzed by multivariate logistic regression analysis. Results  The age， resting heart rate(RHR)， hypertension levels and baPWV of arteriosclerosis group were significantly higher than those of normal group(P＜0.05). The multivariate logistic regression analysis showed that hypertension levels and RHR  were the independent risk factors of baPWV increase for middleaged and elderly patients except for age and smoking  history(OR=3.220，95%CI=1.9125.422，P=0.000；OR=2.226，95%CI=0.8975.524，P=0.085；OR=2.175，95%CI=1.5832.990，P=0.000；OR=3.523，95%CI=1.6547.506，P=0.001).Serum total bilirubin was a protective factor(OR=0.378，95%CI=0.1520.937，P=0.036). Conclusion  Age and smoking， hypertension levels， RHR were the independent risk factors of baPWV increase for middleaged and elderly patients， serum total bilirubin was a protective factor.

Key words: arteriosclerosis, brachialankle pulse wave velocity, risk factor, total bilirubin