Abstract: Latest studies have reported that growth arrestspecific transcript 5 plays an important role in multiple acute and chronic diseases. The current studies report that GAS5,which is identified as a potential novel tumor suppressor gene regulating vital events, such as cell proliferation, apoptosis, and cell cycle, is closely related to the acute myocardial infarction, ischemic stroke, and hypertension. It is expected that GAS5 can be a new target for precise targeting therapy. The paper reviews the relationship between GAS5 and kidney diseases.

Key words: kidney diseases； kidney neoplasms, LncRNA GAS5