Abstract: Complications of patients treated with  maintenance dialysis threaten their quality of life seriously, of which malnutrition，microinflammation and vascular lesion are interrelated,  increasing the morbidity and mortality . Ghrelin can potently stimulate the release of growth hormone, improve the nutritional status of patients and is involved in the pathophysiological process of cardiovascular disease and inflammation. Detection of ghrelin concentrations could make early intervention for maintenance dialysis patients, which is of great significance for clinical auxiliary diagnosis and treatment. This paper reviews the progress on the relationship between ghrelin and chronic kidney disease complications.

Key words: kidney disease, ghrelin; , malnutrition, inflammation; , vascular lesion