Abstract: Objective  To analyze of the clinical data of inpatients with COPD from Respiratory Department of Geriatric Hospital,  and hospitalization  survey on AECOPD and  frailty,  and to study the relationship between frailty and rehospitalized for AECOPD in elderly patients.Methods  A total of 117 inpatients with AECOPD from September 1,2015 to October 31,2018 were prospectively recruited in this study. Diagnosis of frailty was evaluated with CFS within 24 hours of discharge,  and then they were assigned into the frailty group and nonfrailty group. General clinical data,  disease history,  number of comorbidities and drug use were collected. All patients were followed up for 3 months for AECOPD rehospitalization.Results  According to CFS evaluation results,  117 patients were divided into two groups,  frailty group (n=53, 45.3%) and nonfrailty group (n=64, 54.7%).The proportion of patients  age,  cardiac insufficiency and cerebral infarction in frail group was higher than that in nonfrail group(P＜0.05) ,  besides,  the frailty group had larger numbers of comorbidities (≥4),  of medications (＞5) and of COPD level.There were 6 cases of AECOPD hospitalization in nonfrail group within 3 months,  compared with 45 cases in frailty group (P<0.05).Through binary logistic regression analysis,  frailty was the greatest impact on rehospitalization of AECOPD (OR=35.247,  95%CI=10.57117.527,P<0.05).Conclusion  The fragile  elderly people  have higher risk of rehospitalization for AECOPD within three months.

Key words: proteinenergy malnutrition, aged；pulmonary disease, , chronic obstructive