Clinical efficacy of comprehensive pulmonary rehabilitation therapy with full oxygenation in senile patients with COPD at stable stage

doi:10.3969/j.issn.1004-583X.2021.02.008

Abstract

Abstract:

Objective To evaluate the clinical efficacy of comprehensive pulmonary rehabilitation therapy with sufficient oxygenation in senile patients with chronic obstructive pulmonary disease(COPD) at stable stage. Methods A total of 52 patients with COPD aged 65 years or over who were admitted to the department of geriatrics of our hospital from January 2019 to August 2019 were randomly divided into observation group and control group with 26 cases in each group. The control group was given conventional therapy, and the observation group received comprehensive pulmonary rehabilitation therapy with sufficient oxygenation on the basis of conventional treatment in the control group. British Medical Research Council Dyspnea scale (mMRC) score, 6 min walking distance(6MWD), lung function, arterial blood gas analysis, heart rate (HR), and blood oxygen saturation (SaO₂) were compared before treatment and 3 months after treatment in two groups. Results 6MWD, mMRC score, and SaO₂ in observation group were significantly better after 3 months of treatment than before treatment and control group (P<0.01). Partial arterial blood carbon dioxide pressure (PaCO₂), partial oxygen pressure (PaO₂), the percentage of forced breathing volume in the first second (FEV1%), and middle expiratory flow rate (FEF25%-75%) were all improved after 3 months of treatment as compared with before treatment and control group (P<0.05). Conclusion Comprehensive pulmonary rehabilitation therapy with sufficient oxygenation can effectively improve the lung function of senile patients with COPD at stable stage, correct carbon dioxide retention, relieve dyspnea symptoms, and improve the quality of life of senile patients.

Key words: pulmonary disease, chronic obstructive, blood gas analysis, oxygen, rehabilitation

CLC Number:

R563

Xia Xiaoli, Ma Yanping, Wang Yafeng. Clinical efficacy of comprehensive pulmonary rehabilitation therapy with full oxygenation in senile patients with COPD at stable stage[J]. Clinical Focus, 2021, 36(2): 134-138.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2021.02.008

https://huicui.hebmu.edu.cn/EN/Y2021/V36/I2/134

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References 22

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组别	例数	FEV₁%		FEF25%~75%		FEV₁/FVC(%)
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	26	29.0±5.4	28.3±5.7	46.8±5.4	49.2±7.4	63.9±7.5	62.8±9.5
观察组	26	30.6±7.4	34.2±6.2^*	45.2±9.3	52.1±7.6^*	62.8±8.5	66.8±10.5
t值		0.323	3.572	0.333	3.453	0.531	0.386
P值		>0.05	<0.01	>0.05	<0.05	>0.05	>0.05

组别	例数	FEV₁%		FEF25%~75%		FEV₁/FVC(%)
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	26	29.0±5.4	28.3±5.7	46.8±5.4	49.2±7.4	63.9±7.5	62.8±9.5
观察组	26	30.6±7.4	34.2±6.2^*	45.2±9.3	52.1±7.6^*	62.8±8.5	66.8±10.5
t值		0.323	3.572	0.333	3.453	0.531	0.386
P值		>0.05	<0.01	>0.05	<0.05	>0.05	>0.05

组别	例数	6MWT(m)		mMRC(分)
组别	例数	治疗前	治疗后	治疗前	治疗后
对照组	26	192.5±47.2	164.3±37.5	51.2±12.3	49.8±13.7
观察组	26	212.1±41.2	248.0±26.7^*	58.3±13.3	41.3±15.4^*
t值		2.057	-3.184	0.554	4.377
P值		>0.05	<0.01	>0.05	<0.01

组别	例数	6MWT(m)		mMRC(分)
组别	例数	治疗前	治疗后	治疗前	治疗后
对照组	26	192.5±47.2	164.3±37.5	51.2±12.3	49.8±13.7
观察组	26	212.1±41.2	248.0±26.7^*	58.3±13.3	41.3±15.4^*
t值		2.057	-3.184	0.554	4.377
P值		>0.05	<0.01	>0.05	<0.01

组别	例数	PaO₂(mmHg)		PaCO₂(mmHg)
组别	例数	治疗前	治疗后	治疗前	治疗后
对照组	26	53.8±5.2	61.3±7.0	68.9±3.7	65.8±3.3
观察组	26	54.0±5.8	70.6±6.8^*	67.1±4.1	61.1±4.3^*
t值		0.147	7.658	0.241	9.321
P值		>0.05	<0.05	>0.05	<0.05