Abstract: Objective  To investigate the therapeutic effect of Shenmai injection on radiation induced oral mucositis in head and neck neoplasms. Methods  120 cases were diagnosed as head and neck neoplasms, all of which received radiation therapy. The patients were randomly divided into two groups, 60   cases in each group. The control group received routine symptomatic treatment; the observation group was given Shenmai injection more. Both groups were given intensitymodulated radiation therapy: 1.82 to 2.18 Gy once daily, 5 days per week, and the total dose of radiotherapy was 6071.96 Gy. ResultsCompared with control group, the radioactive oral mucositis appeared later and the recovery time was shorter in observation group, with significant difference   (P<0.05).The incidence of moderate and severe radioactive oral mucositis in the two groups was 20% in observation group and 80% in control group, respectively (P<0.01). The average radiotherapy time in observation group was significantly shorter than that in control group, with significant difference(P<0.05).Conclusion  Shenmai injection can significantly alleviate the symptoms of radioactive oral mucositis in patients, ensure that radiotherapy is completed on time,  improve the quality of life, and has good clinical promotion value.

Key words: neoplasms; , radiotherapy dosage；stomatitis; , Shenmai injection