Abstract: Acute kidney injury is common in intensive care units and will significantly increase the mortality of critically ill patients. Evaluation of renal reservation function is important and helpful in initiation of renal replacement therapy and predicting the prognosis. Furosemide stress test has been used for decades since it helps optimize  volume status in acute kidney injury patients and to predict kidney prognosis,  and it can exempt some patients from renal replacement therapy. However,  there is no standardization for furosemide stress test,  and there is a large variation in the choice of patients, the choice of timing, and the choice of dosage and infusion methods. The author reviewed clinical trials in this field and discussed about how to appropriately use furosemide stress test in clinical practice.

Key words: acute kidney injury;  , furosemide stress test