Abstract: Objective  To explore the clinical significance of magnifying endoscopy combined with narrow band imaging in the diagnosis of early esophageal cancer.Methods  This retrospective study was performed in the Second Affiliated Hospital of Zhengzhou University form January 2015 to January 2017. There were 79 cases of early esophageal cancer and precancerous lesions.The relationships between  age and sex,  location,  and endoscopic morphological classification of lesions in the patients were observed and analyzed.Results  MENBI was significantly superior to WLI in identifying the lesion site,  morphology,  pit pattern and microvascular structure in esophagus(P<0.01). The endoscopic diagnosis of the lesions and their postoperative pathological were in a statistically good consistency (kappa coefficient=0.47). These results indicated that IPCL classification had a good predictive value for early esophageal neoplastic disease diagnosis. Conclusion  PCL classification has a good predictive value for early  diagnosis of esophageal neoplastic diseases. According to IPCL classification,  endoscopic diagnosis and postoperative pathological results were in a good consistency.

Key words: esophageal neoplasms, endoscopy, gastrointestinal