Abstract: Objective  To explore the relationship between the local tumor factors and prognosis of esophageal cancer patients who received radical radiotherapy (chemoradiotherapy) based on CT scan. Methods  Analysis was performed in 271 patients with esophageal squamous cell carcinoma who received radical radiotherapy (chemotherapy) and were at clinical stage N0. The local tumor related factors and patients' recurrence was analyzed,  and the factors affecting longterm prognosis of patients were analyzed.Results  GTVD, GTVL, GTVV, GTVV/L and Xray angiography length were the best indicators to predict the recurrence of patients. The optimal boundary values for predicting patients' recurrence were 3.5 cm,  5.5 cm,  28.7 cm3,  4.8 cm2 and 3.5  cm,  respectively. GTVD,  GTVL, clinical T stage, presence or absence of chemotherapy and shortterm efficacy were all independent factors affecting the survival rate of patients. Age,  lesion,  GTVV/L, clinical T stage and shortterm efficacy were all independent factors affecting the  patients'  local control rate.Conclusion  Local tumor related factors of esophageal cancer have impact on the recurrence of patients with clinical N0 esophageal squamous cell carcinoma after radical radiotherapy,  among which GTVD, GTVL and GTVV/L were the independent factors affecting the prognosis.

Key words: esophageal neoplasms, carcinoma, , squamous cells, chemoradiotherapy