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Risk factors  for  HenochSchonlein Purpura in children with abdominal pain as initial symptom

  

  1. Department of Pediatrics,  Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001, China
  • Online:2020-10-20 Published:2020-09-04
  • Contact: Corresponding author:Ye Hong,Email:1013379025@qq.com

Abstract: Objective  To analyze the clinical characteristics of HenochSchonlein Purpura (HSP) in children with abdominal pain as initial symptom, to explore its associated risk factors. Methods  A total of 168 cases of abdominal type of HSP were included.According to whether abdominal pain  was the initial symptom,  they were divided into case group 55 cases and control group 113 cases. In  case group, abdominal pain was the  initial symptom, while in control group, skin rash appeared before abdominal pain. The independent risk factors of HSP  in children with abdominal pain as the initial symptom were explored. Results  In 168 cases of  children with abdominal  HSP,  abdominal pain as the initial symptom accounted for  32.7%(55/168). The rash lagged  behind the onset of abdominal pain for a time range of 1 to 20 days. Significant differences between two groups included fecal occult blood test, admission  body  weight, leukocyte count, platelet count, total protein, albumin and Ddimer. Logistic regression model analysis showed that Ddimer  was  an independent risk factor for HSP children with abdominal pain as initial symptom. Conclusion  For children  with abdominal pain and increased Ddimer, the possibility of  abdominal  HSP should be warned. Ddimer has certain reference value for the  early diagnosis of HSP with abdominal pain as initial symptom.

Key words: purpura, schoenleinhenoch, abdominal pain, children