Abstract: Objective  To analyze the clinical and epidemiological characteristics of corona virus disease2019 (COVID19),  and to provide reference for epidemic prevention and control. Methods  From January 26 to April  5,  2020,  the clinical data of 12 patients with COVID19 in the Second Clinical Observation Department of Chengdu Integrated TCM & Western Medicine Hospital were collected for their basic information,  epidemiological history,  laboratory examinations,  chest CT and so on. Results  There were more males patients than females patients,  with a male to female ratio of 1.4∶1. The disease was mainly concentrated on the middleaged and elderly people older than 40 years old,  and the number of common patients was bigger than that of severe patients,  with a ratio of 1∶5. In the early stage,  the cases were mainly indigenous,  while after midFebruary,  they were mainly imported from foreign countries. 75% of the local cases had a history of Wuhan/Hubei travel or close contact with patients with COVID19,  and the shortest incubation period was 4 days and the longest was 11 days. The main clinical symptoms were fever,  cough,  and cold. There was no significant increase in white blood cells and high sensitivity Creactive protein. The main changes of chest CT were ground glass in both lungs. Compared with severe patients,  the common patients had higher percentages of white blood cells,  neutrophils and lymphocytes,  while they had lower percentages of lymphocytes and hypersensitive Creactive protein,  and lower chest CT scores. Conclusion  COVID19 is mainly concentrated on males,  and people older than 40 years old are at a high risk. Fever is the main clinical symptom. In severe patients,  the hypersensitive Creactive protein significantly increases,  and the chest CT lesions are obvious.

Key words: coronavirus disease 2019, clinical manifestations, epidemiological characteristics