Effects of dense ligation on liver function and hemodynamics in patients with esophageal variceal bleeding

doi:10.3969/j.issn.1004-583X.2021.03.010

Abstract

Abstract:

Objective To investigate the effects of dense ligation on liver function and hemodynamics in patients with esophageal variceal bleeding(EVB). Methods A total of 120 patients of liver cirrhosis with EVB were randomly divided into two groups, the observation group was treated with dense ligation, the control group received sclerotherapy. The liver function and hemodynamic level of patients in two groups were compared. Results ALT, γ-GT and ALP levels of patients of liver cirrhosis with EVB in two groups decreased after treatment, and the observation group was significantly higher than the control group (P<0.05); the blood flow velocity and blood flow in two groups increased after treatment, and the observation group was significantly higher than the control group (P<0.05); The success rate of hemostasis in observation group was higher than that in control group, as well as the incidence of complications was lower than that in the control group (P<0.05). Conclusion Dense ligation is safe and effective in treating patients of liver cirrhosis with EVB, and it can effectively improve the liver function and hemodynamic level of patients.

Key words: ligation, esophageal varicosity, liver function, hemodynamics

CLC Number:

R571.3

Huo Xiaoxia, Niu Weiwei, Han Xu, Zhang Xiaolan. Effects of dense ligation on liver function and hemodynamics in patients with esophageal variceal bleeding[J]. Clinical Focus, 2021, 36(3): 238-241.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2021.03.010

https://huicui.hebmu.edu.cn/EN/Y2021/V36/I3/238

Figures/Tables 3

References 15

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组别	例数	ALT		γ-GT		ALP
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
观察组	60	66.17±4.28	60.15±4.19^#*	101.73±6.43	92.46±6.85^#*	71.20±5.29	62.23±5.47^#*
对照组	60	66.48±4.07	63.43±4.91^#	101.84±6.76	95.95±6.72^#	71.17±5.33	66.26±5.15^#
t值		0.407	3.432	0.092	2.657	0.031	3.234
P值		>0.05	<0.05	>0.05	<0.05	>0.05	<0.05

组别	例数	ALT		γ-GT		ALP
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
观察组	60	66.17±4.28	60.15±4.19^#*	101.73±6.43	92.46±6.85^#*	71.20±5.29	62.23±5.47^#*
对照组	60	66.48±4.07	63.43±4.91^#	101.84±6.76	95.95±6.72^#	71.17±5.33	66.26±5.15^#
t值		0.407	3.432	0.092	2.657	0.031	3.234
P值		>0.05	<0.05	>0.05	<0.05	>0.05	<0.05

组别	例数	门静脉内径(mm)		血流速度(cm/s)		血流量(ml/min)
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
观察组	60	13.41±1.23	13.43±1.14	11.03±2.49	13.51±2.75^#*	1001.21±674.25	1315.24±732.67^#*
对照组	60	13.42±1.57	13.45±1.61	11.04±2.70	12.67±2.92^#	1003.12±669.73	1187.36±703.85^#
t值		0.039	0.598	0.021	2.591	0.016	6.734
P值		>0.05	>0.05	>0.05	<0.05	>0.05	<0.05

组别	例数	门静脉内径(mm)		血流速度(cm/s)		血流量(ml/min)
组别	例数	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
观察组	60	13.41±1.23	13.43±1.14	11.03±2.49	13.51±2.75^#*	1001.21±674.25	1315.24±732.67^#*
对照组	60	13.42±1.57	13.45±1.61	11.04±2.70	12.67±2.92^#	1003.12±669.73	1187.36±703.85^#
t值		0.039	0.598	0.021	2.591	0.016	6.734
P值		>0.05	>0.05	>0.05	<0.05	>0.05	<0.05

组别	例数	止血成功	发热	胸痛	腹胀
观察组	60	56(93.33)	5(8.33)	6(10.00)	8(13.33)
对照组	60	52(86.67)	17(28.33)	18(30.00)	22(36.67)
χ²值		4.925	6.301	5.926	5.883
P值		0.036	0.003	0.013	0.021