Abstract: Atherosclerosis is the major cause of ischemic cerebrovascular disease.Traditionally, the degree of responsibility artery stenosis has always been a major factor for predicting recurrence in stroke patients. The CICAS study revealed that the annual recurrence rate of stroke patients with a narrowed degree of less than 50% was between 0.58%  and  5.88%, indicating that the degree of stenosis did not necessarily determine the dangerous arteries of the patients. Therefore, we should pay more attention to the blood flow of the responsible artery, rather than the degree of arterial stenosis. The concept of flow fraction reserve (FFR) is introduced from the cardiovascular field, which removes the traditional concept of coronary stenosis, and can also be applied to the study of cerebrovascular disease. Based on the similarity between coronary heart disease and stroke, coronary circulation may provide the best reference for FFR measurement of cerebral vessels. The degree of stenosis of contrast examination can not tell whether the degree of stenosis is accompanied by changes in hemodynamics, thus reducing the value of functional assessment and inaccurately judging the high risk of plaque. Paying attention to the state of hemodynamics may play a patienttailored role in the treatment of ischemic stroke patients.

Key words: brain infarction, hemodynamics, fractional flow reserve, myocardial