Abstract: Objective  To study the risk factors for oneyear poor prognosis in patients with acute cerebral infarction (ACI). Methods  From January 20,  2014 to December 30,  2017,   3 252 ACI patients who were admitted to hospital continuously and met the inclusion criteria were selected. They were divided into good prognosis group (mRs score≤2),  poor prognosis group (mRs score > 2) according to the modified Rankin scale (mRs) of oneyear followup. The former involved  2 912  patients,  and the latter included 340 patients.  The risk factors related to oneyear poor prognosis of ACI patients were analyzed. Results  There were statistically significant differences between poor prognosis group and good prognosis group in terms of  age,  history of diabetes,  hyperlipidemia,  stroke,  atrial fibrillation,  coronary heart disease,  smoking,  drinking,  carotid artery plaque formation and antiplatelet drug use,  education degree,  systolic blood pressure,  fasting glucose,  triglycerides,  highdensity lipoprotein cholesterol,  lipoprotein a,   creatinine,  cystatin C,  prothrombin time,  international standardization rate,  fibrinogen,  homocysteine and NIHSS score within 24hours of admission (P<0.05). Multivariate Logistic regression analysis showed that the independent risk factors for oneyear poor prognosis in ACI patients were age,  previous stroke,  systolic blood pressure,  creatinine,  fibrinogen,  and NIHSS score within 24 hours of admission. Conclusion  The independent risk factors for oneyear poor prognosis in ACI patients included age of onset,  previous stroke,  systolic blood pressure,  creatinine,  fibrinogen,  and NIHSS score within 24 hours of  admission. Early identification and attention to the population with poor prognosis and active prevention can reduce the risk of poor prognosis.

Key words: brain infarction, prognosis, risk factors