Gabapentin treatment in olanzapine-induced restless legs syndrome: Two cases report and literature review

doi:10.3969/j.issn.1004-583X.2023.01.010

Abstract

Abstract:

Objective To explore the therapeutic efficacy of gabapentin on olanzapine-induced restless legs syndrome (RLS). Methods The clinical data, diagnosis and treatment of 2 cases of olanzapine-induced RLS treated with gabapentin were analyzed retrospectively, and the related literatures were reviewed. Results During the treatment with olanzapine, two patients with schizophrenia both suffered from unspeakable discomfort in their lower limbs at night. They uncontrollably wanted to move their legs and got up and walked, otherwise they would feel uncomfortable and difficult to fall asleep. Patting with their hands or walking out of bed could alleviate the discomfort. They were diagnosed as olanzapine-induced RLS and successfully treated with gabapentin. Conclusion Gabapentin can be used to treat olanzapine-induced RLS.

Key words: restless legs syndrome, schizophrenia, olanzapine, gabapentin

CLC Number:

R742.89

Sun Zhenxiao, Zhao Lin. Gabapentin treatment in olanzapine-induced restless legs syndrome: Two cases report and literature review[J]. Clinical Focus, 2023, 38(1): 68-70.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2023.01.010

https://huicui.hebmu.edu.cn/EN/Y2023/V38/I1/68

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