Cryptococcal meningoencephalitis with unstable gait as the initial symptom: A case report

doi:10.3969/j.issn.1004-583X.2023.03.012

Abstract

Abstract:

Objective To investigate the clinical characteristics of patients with cryptococcal meningoencephalitis with unstable gait as the initial symptom. Methods The clinical datas of a cryptococcal meningoencephalitis patient with unstable gait as the initial symptom were analyzed.Results A 45-year-old male presented with unstable gait two years ago, and the symptoms worsened progressively, complicated with decreased memory and delayed response. Brain MR scans showed dilation of the ventricular system, and cerebrospinal fluid examination revealed cryptococcal infection. After treatment with amphotericin B and fluorocytosine, the clinical symptoms improved. Conclusion Cryptococcal meningoencephalitis usually has an insidious onset, and unstable gait may be the initial symptom, which should be paid attention in clinical practice.

Key words: meningitis, cryptococcal, unstable gait, initial symptom

CLC Number:

R515.2

Wang Yao, Huang Pengru, Zeng Zhaohao, Luo Hong, Cen Haimei, Luo Bin, Zhang Yu. Cryptococcal meningoencephalitis with unstable gait as the initial symptom: A case report[J]. Clinical Focus, 2023, 38(3): 260-263.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2023.03.012

https://huicui.hebmu.edu.cn/EN/Y2023/V38/I3/260

Figures/Tables 4

References 13

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日期	压力 (mmH₂O)	糖 (mmol/L)	氯 (mmol/L)	蛋白 (mg/L)	白细胞 (×10⁶/L)	单个核比例 (%)	红细胞 (×10⁶/L)	隐球菌培养	血糖 (mmol/L)
2020-05-06	145	2.65	109.5	3001	64	94	100	-	9.8
2020-05-15	150	2.48	104.1	2821	14	93	0	+	10.5
2020-05-25	85	2.81	109.3	3265	221	90	100	-	12.8
2020-06-01	78	1.82	121.6	2368	51	99	100	-	6.2
2020-06-08	95	3.36	124.6	2290	10	98	0	-	7.9
2020-06-16	55	3.45	125.8	2126	17	88	100	-	7.2
2020-06-25	测不出	6.97	134.4	1873	23	100	1000	-	21.6

日期	压力 (mmH₂O)	糖 (mmol/L)	氯 (mmol/L)	蛋白 (mg/L)	白细胞 (×10⁶/L)	单个核比例 (%)	红细胞 (×10⁶/L)	隐球菌培养	血糖 (mmol/L)
2020-05-06	145	2.65	109.5	3001	64	94	100	-	9.8
2020-05-15	150	2.48	104.1	2821	14	93	0	+	10.5
2020-05-25	85	2.81	109.3	3265	221	90	100	-	12.8
2020-06-01	78	1.82	121.6	2368	51	99	100	-	6.2
2020-06-08	95	3.36	124.6	2290	10	98	0	-	7.9
2020-06-16	55	3.45	125.8	2126	17	88	100	-	7.2
2020-06-25	测不出	6.97	134.4	1873	23	100	1000	-	21.6